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Clinical Trial Summary

The aim of this study is to assess surgical management and outcome of Tethered cord syndrome


Clinical Trial Description

Tethered cord syndrome (TCS) is a developmental abnormality of the neuroaxis which is usually diagnosed in childhood. The actual tethering has been attributed to a variety of pathologic entities, including a thickened tight filum terminale , intradural lipomas with or without a connecting extradural component, intradural fibrous adhesions, diastematomyelia, and adherence of the neural placode following previous closure of a myelomeningocele. However, sufficient differences in the mode of onset, clinical manifestations, and outcome exist between pediatric and adolescent patients with tethered cord to warrant a more detailed analysis of the adult syndrome. The most problematic technical consideration in surgery for the release of the tethered cord is how to preserve functioning neural elements and rebuild the dural sac to avoid CSF leak. The purpose of this study is to review causes of Tethered cord, clinical presentation, diagnostic tools, treatment options and outcome in school-aged children, adolescents, and young adults with Tethered cord. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05579795
Study type Observational
Source Assiut University
Contact Amr Gamal Hussein, GP
Phone 01067651618
Email amrgamalz@yahoo.com
Status Not yet recruiting
Phase
Start date November 2, 2022
Completion date December 2, 2024

See also
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Recruiting NCT05163899 - Investigation of Surgical Sectioning of the Filum Terminale in Treating Occult Tethered Cord Syndrome Patients Phase 2
Recruiting NCT04738539 - Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies
Recruiting NCT03262844 - Efficacy and Safety of Nerve Root Axial Decompression Surgery in The Treatment of Tethered Cord Syndrome N/A