Test if Increased Chewing Will Increased Microbiota SCFA Production Clinical Trial
Official title:
Effects of Increased Chewing Efficiency on the Gut Microbiome
This study is designed to test the effects of chewing efficiency on human gut microbiome composition and function.
Our working hypothesis is that increased chewing will lead to an increase in short-chain fatty acid production We further expect this effect to lead to a detectable decrease in fecal particle size and distinct changes in gut microbial community composition. Here, we will explore this hypothesis using a fixed-order within-subjects study design in a group of healthy participants. Each participant will have one week of normal dietary habits and one week of increased chewing time. We will collect stool samples three times per week in order to measure microbial abundance and metabolism. ;