The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy

Status Recruiting

Clinical Trial Summary

Clinical Trial Description

Portal vein hypertension is associated with post-hepatectomy liver failure in patients with liver cirrhosis. Our previous study found that bolus injection of 1 mg terlipressin immediately after hepatectomy decreased portal vein pressure, and post-operative continuous use of terlipressin decreased the amount of abdominal drain. In this multicenter randomized controlled study, we aim to evaluate the effects of terlipressin in the patients who underwent liver resection complicated by portal vein hypertension. The primary outcome is the total abdominal drain on postoperative day (POD) 1 to 3. The secondary outcomes are: (1) the incidence of post-hepatectomy liver failure; (2) post-operative acute kidney injury; (3) the side effects of terlipressin. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04221672
Study type	Interventional
Source	Shanghai Zhongshan Hospital
Contact	Xiao-Dong Zhu, MD&PhD
Phone	+862164041990
Email	zhuxiaodong@gmail.com
Status	Recruiting
Phase	Phase 3
Start date	November 7, 2019
Completion date	December 30, 2020

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