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Tendon Injuries clinical trials

View clinical trials related to Tendon Injuries.

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NCT ID: NCT03632304 Completed - Anesthesia, Local Clinical Trials

Local Anesthesia With Minimal Sedation and Brachial Plexus Block in Hand Surgery

Start date: August 17, 2018
Phase: N/A
Study type: Interventional

A major innovation in hand surgery in the last decade is the popularization of Wide Awake Hand Surgery (WAHS). This technique consists of numbing the surgical area with local anesthesia with epinephrine and allowing the patient to actively move their hand intra-operatively to assess the strength and quality of repairs or fixations. Despite its theoretical advantages, the application in clinical practice has seldom spread further than simple hand operations, such as carpal tunnel and trigger finger releases. In many institutions, the current standard of care for hand surgery is the brachial plexus block. The primary objective of the study to directly compare the effects of local anesthesia with minimal sedation, performed by the surgeon, and the brachial plexus block, performed by the anesthesiologist, on patient-reported quality of recovery. Currently, there are no studies in the surgical literature directly comparing patient-reported quality of recovery, post-operative pain control, or time efficiency between local anesthesia and the brachial plexus block in hand surgery. This lack of information is a major impediment to the acceptance and adoption of a simple yet effective anesthesia technique that may increase patient satisfaction and time efficiency in the operating room. This proposed prospective randomized controlled study will quantitatively compare local anesthesia and brachial plexus block on three fronts: 1) patient-reported recovery at 24-hours post-surgery using the validated Quality of Recovery 15 score (QoR-15), 2) post-operative pain and opioid use at 24-hours post-surgery, and 3) nonsurgical time (defined as the time elapsed from one surgery's end time to the next surgery's start time) as a metric for turnover efficiency. The investigators hypothesize that patients randomized to the local anesthesia group will have a more positive recovery experience, a similar pain profile compared to the brachial plexus block despite common beliefs, and a shorter anesthesia-related and nonsurgical time. The importance of patient-centered care cannot be understated in a successful and high-quality health care system. The results of this study will provide valuable information regarding the patient experience during their post- operative recovery.

NCT ID: NCT03622372 Active, not recruiting - Clinical trials for Tendon Injury - Hand

Zone 2 Flexor Tendon Repair With CoNextions TR Implant System

Start date: June 21, 2018
Phase: Phase 3
Study type: Interventional

Prospective, randomised, controlled trial of a novel implant intended for use during surgical repair of lacerated Zone 2 flexor digitorum profundus tendons.

NCT ID: NCT03449082 Active, not recruiting - Clinical trials for Lateral Epicondylitis

Treatment of Intractable Common Extensor Tendon Injury Using Mesenchymal Stem Cells (Allo-ASC)

Start date: May 4, 2018
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety of intra-tendon injection of allogeneic adipose-derived mesenchymal stem cells (Allo-ASC) in intractable common extensor tendinosis patients in comparison with a control treatment.

NCT ID: NCT03401177 Completed - Inflammation Clinical Trials

Treatment of Early Phase Achilles Tendinopathy - the Effect of NSAIDs

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

this study evaluates the addition of initial short term NSAID treatment to physiotherapy prescribed exercise treatment in patient with early phase tendinopathy. Half of the participants will initially receive NSAID (naproxen) for 7 days, while the other half will receive a placebo, where after both groups will be subjected to 3 months heavy slow resistance training.

NCT ID: NCT03362424 Suspended - Rotator Cuff Tear Clinical Trials

Mesenchymal Stem Cells in Rotator Cuff Repair

Start date: November 1, 2020
Phase: Phase 2
Study type: Interventional

Randomized clinical study involving 44 patients, evaluating the effect of mesenchymal cells on rotator cuff repair. The primary outcome will be post-operative MRI tendon integrity and secondary outcomes clinical assessment by the UCLA and American Shoulder and Elbow Surgeons (ASES) scales and pain by visual analog scale (VAS).

NCT ID: NCT03311997 Completed - Clinical trials for Hamstring Tendon Injury

The Proximal Hamstring Avulsion Clinical Trial - Operative or Nonoperative Treatment

PHACT
Start date: October 24, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to provide reliable evidence on how to best treat proximal hamstrings avulsions, and our primary aim is to compare the reported outcome of patients treated non-operatively with patients treated with suture anchor reattachment of the tendons using the Perth Hamstrings Assessment Tool (PHAT) at 24 months.

NCT ID: NCT03307499 Completed - Tendinopathy Clinical Trials

NeoPatch Used as Adjunct in Foot and Ankle Tendon Surgery

Start date: September 21, 2017
Phase: N/A
Study type: Interventional

This study is a prospective, single center, postmarket study to evaluate the safety and effectiveness of NeoPatch used as a tissue cover in foot and ankle tendon revision and repair surgery.

NCT ID: NCT03135340 Not yet recruiting - Clinical trials for Tendon Injury - Hand

Wide-Awake Local Anesthesia vs. Regional/General Anesthesia for Flexor Tendon Repair

Start date: August 2017
Phase: N/A
Study type: Interventional

Wide-awake hand surgery with local anesthetic, no tourniquet and no sedation (WALANT) is increasingly utilized. Conventional anesthesia for hand surgery involves a patient with a block, unable to perform motor function in the arm, and with patient either intubated or sedated, unable to follow surgeon instructions intra-operatively. Flexor tendon repair with a wide awake and cooperative patient is routinely performed successfully at some centres. This method provides several potential benefits including being able to have the patient actively flex the digit and visualize the repair site to assess for any tendon gapping at the repair site, ensure adequate approximation, gliding and absence of triggering. There have not been any prospectively collected randomized controlled trials comparing wide awake vs. regional/general anesthesia in flexor tendon repair. The purpose of our study is to assess for differences in early outcomes including stiffness, patient satisfaction and early complications in wide-awake anesthesia when compared to general/regional anesthesia for flexor tendon repair in zones I and II. Our hypothesis is that there is a lower complication rate and better outcomes when using wide-awake flexor tendon repair.

NCT ID: NCT02805751 Completed - Clinical trials for Achilles Tendon Rupture

Early Controlled Loading on Conservative Treated Achilles Tendon Ruptures

Start date: October 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to measure the mechanical properties of the tendon after conservative treated Achilles tendon ruptures with or without early controlled loading. This is done in a randomized trial and the mechanical properties are measured using roentgen stereometric analysis (RSA). The hypothesis is that early weightbearing improves mechanical properties of conservative treated Achilles tendon ruptures without causing elongation of the tendon.

NCT ID: NCT02725346 Active, not recruiting - Clinical trials for Shoulder Impingement Syndrome

ArthroPlanner: A Surgical Planning Solution for Acromioplasty

Start date: July 2015
Phase: N/A
Study type: Interventional

A computer-assisted solution for acromioplasty is presented. The software allows surgeons to better plan the surgical procedure by visualizing dynamic simulation of the patient's shoulder joint during everyday activities. Impingements are dynamically detected and the exact location and amount of bone to be resected is precisely computed. As a result, the success of the acromioplasty does not only rely on the surgeon's experience or previous recommendations, but on quantitative data. Although the clinical validation of this 3D planning support is currently under evaluation, it may allow to recover more effectively postoperative joint mobility, to get a better relationship with pain and a better healing rate of the rotator cuff tendons.