Temporomandibular Disorder Clinical Trial
Official title:
Efficacy and Safety of JHG002(Hominis Placenta, 紫河車) Therapy for Chronic Temporomandibular Joint Dysfunction: A Multicenter Randomized Controlled Trial)
This study is a 2-arm parallel, assessor blinded, multi-centre, randomised controlled trial.
From 2 hospitals of Korean medicine, we will enrol 82 chronic TMD patients in Axis 1, Group Ⅰ according to RDC/TMD diagnostic criteria, and randomly allocate 41 patients each to an HPP group and a physical therapy (PT) group. Treatment will be administered in 10 rounds, after which there will be 4 follow-up visits (6, 9, 13, and 25 weeks from baseline). The primary end point is 6 weeks after baseline, and the primary outcome is the difference in Visual analogue scale (VAS) score for temporomandibular pain between baseline and Week 6. Secondary outcomes will be Numeric rating scale (NRS) scores for temporomandibular pain and discomfort, temporomandibular joint range of motion, Korean version of Beck's Depression Index-Ⅱ(K-BDI-II), Jaw Functional Limitation Scale (JFLS), Patien Global Impression of Change(PGIC), and quality of life. Using data on adverse events and cost-effectiveness in the two groups, we will perform a safety assessment and a cost-effectiveness analysis (economic assessment). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05006963 -
Tele-Rehabilitation in Patients With Temporomandibular Dysfunction
|
N/A | |
| Completed |
NCT04102306 -
Assessing Motor Imagery Ability of Tongue and Mouth in Subjects With and With no Temporomandibular Disorders
|
||
| Not yet recruiting |
NCT05297604 -
Non-Invasive Intravascular Laser Irradiation Of Blood In The Treatment Of Children With Temporomandibular Disorders
|
Phase 2 | |
| Recruiting |
NCT06035341 -
The Association Between Temporomandibular Disorders and Sacroiliac Joint Dysfunction
|
N/A | |
| Recruiting |
NCT03849534 -
Treatment of Temporomandibular Disorders in Children and Adolsecents
|
N/A | |
| Not yet recruiting |
NCT05021874 -
The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.
|
N/A | |
| Recruiting |
NCT05232604 -
How is Aerobic Exercise Compared to Localized Pain Relief Exercises in Patients With Jaw Pain and Neck Pain?
|
N/A | |
| Completed |
NCT04557878 -
Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction
|
Phase 2 | |
| Completed |
NCT03726060 -
Effectiveness of Physical Teraphy in the Treatment of Myogenic Temporomandibular Disorders
|
N/A | |
| Not yet recruiting |
NCT06123351 -
Forward Head Posture Correction Impact on Temporomandibular Dysfunction
|
N/A | |
| Completed |
NCT03619889 -
The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder
|
N/A | |
| Completed |
NCT01000389 -
A Clinical Trial of the Optimal Treatment Period and Long-term Efficacy of Functional Electrical Stimulation (FES) on Sleep Bruxism
|
N/A | |
| Completed |
NCT00743223 -
The Frequency Forward Head Posture in Subjects With Temporomandibular Disorder
|
N/A | |
| Completed |
NCT03300297 -
Cervical Spine Thrust Joint Manipulation for Temporomandibular Disorder
|
N/A | |
| Completed |
NCT06065826 -
Forward Head Posture and Myogenic TMD Association in Smartphone Overuse
|
||
| Recruiting |
NCT03696706 -
Photobiomodulation With Red and Infrared LED Device for Temporomandibular Dysfunction
|
Phase 2 | |
| Completed |
NCT04041271 -
Jaw Kinematics and Muscle Activation in Patients With Non-specific Chronic Neck Pain
|
||
| Recruiting |
NCT03096301 -
Photobiomodulation in Temporomandibular Disorder
|
N/A | |
| Not yet recruiting |
NCT06052722 -
The Relationship of Premenstrual Syndrome and Primary Dysmenorrhea With Severity of Temporomandibular Disorders
|
N/A | |
| Recruiting |
NCT05305833 -
Stem Cells and Stromal Vascular Fraction for Temporomandibular Joint Disease
|
Phase 1/Phase 2 |