Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars

Status Not yet recruiting

Clinical Trial Summary

This research study delves into the effectiveness of bioactive and non-bioactive restorative systems in deep carious permanent molars treated with selective caries removal. Selective caries removal techniques aim to preserve as much healthy tooth structure as possible while effectively eliminating carious tissue. The study investigates how the choice of restorative material influences the outcomes of selective caries removal procedures in deep carious lesions. By assessing factors such as restoration integrity, pulpal response, and long-term success rates, the research seeks to provide evidence-based insights into the comparative performance of bioactive and non-bioactive restorative systems in this clinical context.

Clinical Trial Description

Deep carious lesions in permanent molars present a significant challenge in restorative dentistry. Traditional approaches to caries removal often involve the removal of excessive healthy tooth structure, leading to weakened teeth and potential pulp exposure. Selective caries removal techniques aim to preserve as much healthy tooth structure as possible while effectively eliminating carious tissue, offering a conservative alternative to traditional methods. In recent years, bioactive restorative materials have emerged as promising alternatives to conventional non-bioactive materials. Bioactive materials are designed to interact with the biological environment, promoting remineralization and potentially enhancing the longevity of restorations. However, limited evidence exists comparing the efficacy of bioactive and non-bioactive restorative systems in deep carious lesions treated with selective caries removal. This study is designed as a prospective, randomized controlled trial. Patients presenting with deep carious lesions in permanent molars will be randomly allocated to receive either a bioactive or non-bioactive restorative system following selective caries removal. Baseline demographic and clinical data will be recorded for each participant. Clinical evaluations will be conducted at regular intervals over a follow-up period of months. Outcome measures will include restoration integrity (e.g retention, marginal adaptation), pulpal response (e.g., sensitivity, vitality). ;

Study Design

Related Conditions & MeSH terms

Caries; Dentin
Deep Caries
Dental Caries
Dental Diseases
Dental Restoration Failure of Marginal Integrity
Stomatognathic Diseases
Teeth; Lesion
Tooth Decay
Tooth Demineralization
Tooth Diseases

Clinical Trial Details

NCT number	NCT06348953
Study type	Interventional
Source	Cairo University
Contact
Status	Not yet recruiting
Phase	N/A
Start date	April 2024
Completion date	November 2025

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04127929` - Investigation of Glass Carbomer Performance	N/A
Completed	`NCT04769882` - Er:YAG Laser Effects on Microbial Population in Conservative Dentistry	N/A
Completed	`NCT04971317` - The Influence of Simple, Low-Cost Chemistry Intervention Videos: A Randomized Trial of Children's Preferences for Sugar-Sweetened Beverages	N/A
Active, not recruiting	`NCT04475679` - Clinical Evaluation of Adhese Universal DC in the Indirect Restorative Therapy	N/A
Completed	`NCT05438381` - Comparison of Clinical and Radiographic Outcomes of SMART Technique vs ART in Primary Molars	N/A
Not yet recruiting	`NCT03037814` - Clinical Performance of Restorative Materials in Primary Teeth	N/A
Active, not recruiting	`NCT05202665` - Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion	N/A
Terminated	`NCT01147835` - Herbal Lollipops on Oral Bacterial Levels and DMFT/Dmft Scores of Children With Asthma Using Inhalers	N/A
Not yet recruiting	`NCT04033263` - Maintaining Oral Health With Bio-products	N/A
Enrolling by invitation	`NCT04438252` - Evaluation of Reliability of CarieScan PRO Compared With Digital Radiograph and ICDAS-II in Detection of Carious Lesions	N/A
Not yet recruiting	`NCT03609034` - Knowledge, Attitude and Practice of a Group of Egyptian Dental Interns Toward Caries Risk Assessment
Completed	`NCT02912000` - TEACH: Technology Evaluation to Address Child Health	N/A
Completed	`NCT02473107` - Impact of Detecting Initial and Active Caries Lesions in Primary Teeth	N/A
Active, not recruiting	`NCT02537184` - Impact of Two Recall Intervals on Dental Caries Incidence and Other Outcomes of Preschool Children	N/A
Completed	`NCT01950546` - Nanosilver Fluoride to Prevent Dental Biofilms Growth	Phase 1
Recruiting	`NCT02734420` - Effect of Photodynamic Therapy With Low-level Laser on Infected Dentin in Primary Teeth: A Controlled Clinical Trial	Phase 1
Completed	`NCT02020681` - Effect of Curodont Repair or Placebo on the Remineralisation in Patients With Class 5 Carious Lesions	N/A
Completed	`NCT02426619` - Arresting Active Dental Caries in Preschool Children by Topical Fluorides	Phase 2/Phase 3
Completed	`NCT02234609` - Effectiveness of Modified Class IV Atraumatic Restorative Treatment	N/A
Completed	`NCT01623362` - Evaluation of a Low Fluoride Dentifrice for Caries Control	Phase 3