Nanofat Versus Platelet Poor Plasma Gel for Infraorbital Rejuvenation

Tear Trough Eyelid Deformity Clinical Trial

Official title:

Nanofat Versus Platelet Poor Plasma Gel for Infraorbital Rejuvenation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06318091
• Other study ID #: MS.21.09.1640
• Status: Completed
• Phase: Phase 1
• Start date: June 1, 2021
• Est. completion date: June 1, 2023

Study information

• Verified date: March 2024
• Source: Mansoura University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

this study was conducted for evaluation of the clinical efficacy, safety, and potential side effects of platelet poor plasma gel versus nonfat injection in infraorbital rejuvenation

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: June 1, 2023
• Est. primary completion date: June 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• all patients with infraorbital dark circles

Exclusion Criteria:

• pregnancy

• breast feeding

• infectious disorders

Related Conditions & MeSH terms

• Congenital Abnormalities
• Tear Trough Eyelid Deformity

Intervention

Biological:
• platelet poor plasma gel
injection of platelet poor plasma gel in the dark circles around the eye to rejuvenate and improve pigmentation
• nanofat
injection of nanofat in the dark circles around the eye to rejuvenate and improve pigmentation

Locations

Country	Name	City	State
Egypt	Manousra University, Faculty of Medicine	Mansoura	Dakahlia

Sponsors (1)

Lead Sponsor	Collaborator
Mansoura University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the degree of changes in the skin texture and homogeneity	the degree of changes in the skin texture and homogeneity was assessed using the five grades scale according to percentage of change in skin surface smoothness and color uniformity (1: much worse if deterioration >25%, 2: worse if deterioration <25%, 3: slightly improved if improvement <25%, 4: improved if improvement = 25%-50%, and 5: greatly improved if improvement >50%).	3 months