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Tachycardia, Ventricular clinical trials

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NCT ID: NCT01590979 Completed - Hemorrhage Clinical Trials

Randomized Double Blind Control Trial on Effects of Ranolazine on New Onset Atrial Fibrillation

Start date: April 2012
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the prophylactic effects of Ranolazine on new onset atrial fibrillation in post-operative coronary artery bypass graft and valve surgery patient population at Staten Island University hospital.

NCT ID: NCT01572246 Completed - Heart Failure Clinical Trials

Effects of Monopolar Electrocautery Use During Surgery on Implanted Cardiac Defibrillators

Start date: May 2012
Phase: N/A
Study type: Observational

This observational protocol will evaluate the effects of monopolar electrocautery (ME) on implantable cardioverter defibrillators (ICDs) in patients undergoing surgery. ME can cause electromagnetic interference (EMI) leading to ICD damage or inadvertent ICD discharge (shocks). Recommended practice calls for the preoperative reprogramming of ICDs when ME will be used to prevent patients from receiving inadvertent shocks. This requires the presence of someone trained in ICD programming, but a trained person is not always readily available. In this study the investigators will reprogram ICDs prior to surgery according to current practice, but will also record what would have happened had the ICD reprogramming not occurred ("detection on" but "therapy off"). In addition, the investigators will evaluate the effect of the location of the electrosurgery unit (ESU) return pad on the incidence of EMI. The investigators hypothesize that directing the current return path away from the ICD will result in lower EMI rates than previously described.

NCT ID: NCT01492764 Completed - Clinical trials for Ventricular Tachyarrhythmias

Ablation of Ventricular Fibrillation by Accurate Targeting of Arrhythmogenic Regions (AVATAR)

AVATAR
Start date: June 2011
Phase:
Study type: Observational

This study will test the hypothesis that many human heart rhythm disorders are caused by small localized sources, where brief ablation may successfully eliminate the heart rhythm disorder.

NCT ID: NCT01446965 Completed - Clinical trials for Myocardial Infarction

Vest Prevention of Early Sudden Death Trial and VEST Registry

VEST
Start date: July 2008
Phase: N/A
Study type: Interventional

This study explores the hypothesis that wearable defibrillators can impact mortality by reducing sudden death during the first three months after a heart attack in persons with high risk for life-threatening arrhythmias.

NCT ID: NCT01326624 Completed - Heart Failure Clinical Trials

Study of the Wearable Defibrillator in Heart-Failure Patients

SWIFT
Start date: March 2011
Phase: N/A
Study type: Observational

The purpose of the study is to evaluate the safety and efficacy of wearable defibrillator use in patients with left ventricular dysfunction or advanced heart failure symptoms, who have a high-risk for sudden cardiac death but are either not eligible for an implantable defibrillator under current guidelines or are not able to receive the device due to their condition.

NCT ID: NCT01294267 Completed - Clinical trials for Ventricular Tachycardia

Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation

PERMIT1
Start date: September 2010
Phase: N/A
Study type: Interventional

The purpose of this research study is to evaluate the safety and feasibility of the Impella 2.5 Circulatory Support System for use during mapping and ablation of ventricular tachycardia in the setting of Ventricular dysfunction.

NCT ID: NCT01282918 Completed - Clinical trials for Ventricular Tachyarrhythmia

NORDIC ICD (Cardioverter Defibrillator Implantation) Trial

Start date: February 2011
Phase: N/A
Study type: Interventional

The purpose of the NORDIC ICD study is to evaluate whether ICD implantation without intra-operative DF testing is non-inferior to ICD implantation with intra-operative DF testing regarding the efficacy of the first ICD shock for the treatment of true spontaneous ventricular tachyarrhythmias.

NCT ID: NCT01250912 Completed - Clinical trials for Ventricular Tachycardia

Imaging With a Radio Tracer to Guide VT Ablations

Start date: March 2010
Phase: N/A
Study type: Interventional

Some patients are at risk for life-threatening fast heart rates. These can frequently be treated by using a catheter inside the heart to burn away the cells that create the fast heart rates. The purpose of this study is to image the nerves inside the heart of those patients. The investigators want to find out if abnormalities in the nervous system in the heart can help the physician to find the area that needs to be burnt away.

NCT ID: NCT01182389 Completed - Clinical trials for Ventricular Tachycardia

A Study of Early Robotic Ablation by Substrate Elimination of Ventricular Tachycardia

ERASE-VT
Start date: October 2011
Phase: N/A
Study type: Interventional

Ventricular tachycardia (VT) is an abnormal rapid heartbeat which occurs after a heart attack and can cause sudden death. Patients at risk of this rhythm disturbance usually receive an implantable cardioverter defibrillator (ICD) that can prevent death by returning the heart's rhythm back to normal by electrically stimulating the heart but in doing so gives the patient painful and debilitating shocks. The first ICD shock after implantation appears to be a powerful predictor of subsequent shock therapy as well as being a predictor of of increased mortality in patients with primary prevention ICDs. In patients who receive repeated shocks VT ablation is performed to 'burn' the abnormal area of the heart that causes the problem. However, it is often only performed as a last resort as it is technically challenging. We believe that performing VT ablation using the robotic system early after the first episode of VT after ICD implantation, may reduce the number of painful shocks received by the patient and possibly increase life expectancy and quality of life. 200 patients from 5 european countries will be recruited in a prospective, open, randomised trial. Eligible, consenting patients who have experienced their first episode of VT since ICD implantation, will be randomised in a 1:1 manner into treatment arms of either VT ablation or standard 'conventional' therapy and followed-up every 4 months over two years to assess the number of subsequent ICD shocks, hospitalisation, mortality and quality of life.

NCT ID: NCT01169896 Completed - Clinical trials for Ventricular Tachycardia

Impact of Ventricular Pacing in Unselected ICD/CRT-D Patients

FIRST
Start date: November 2007
Phase: N/A
Study type: Observational

Observational study is evaluating Ventricular Tachycardia (VT)/Ventricular Fibrillation (VF) thérapies as a function of ventricular pacing