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T2DM (Type 2 Diabetes Mellitus) clinical trials

View clinical trials related to T2DM (Type 2 Diabetes Mellitus).

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NCT ID: NCT06055582 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

To Study the Effects of Mango Ingestion in T2DM and Non-diabetic Subjects.

Start date: February 11, 2022
Phase: N/A
Study type: Interventional

T2DM patient will be recruited from endocrine OPD 1. Clinical History and Examination: 1. General Physical Examination: - Height (cm) - weight (kg) - BMI (kg/m2) - Blood Pressure (mmHg) 2. Anthropometry: Circumferences and skinfold thickness will be recorded for the patients in the following manner. Circumferences: - Waist circumference (cm) - Hip circumference (cm) - Mid-arm circumference (cm) - Mid-thigh circumference (cm) 3. Skin fold thickness: Skin fold thickness will be measured by using (LANGE skin fold calipers) (to nearest of 1 mm) at the following sites - Biceps (mm) - Triceps (mm) - Thigh (mm) - Calf (mm) - Sub scapular (mm) - Supra-iliac (mm) - Anterior axillary fold. (mm) 2. Biochemical Test: The biochemical analysis will be done using ELISA kit or commercially available kits - Blood glucose (mg/dL) - HbA1c (%) - Serum insulin (μIU/mL) - Total Cholestrol (mg/dl) - Triglyceride (mg/dl) - Fructosamine (umol/L) - Adiponectin (µg/ml) -- HOMA-IR 3. Body Composition Analysis (TANITA)

NCT ID: NCT05983289 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Single Escalating Dose Study Of HSK7653 In Healthy Subjects

Start date: May 8, 2018
Phase: Phase 1
Study type: Interventional

To evaluate the safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of single dose of HSK7653 tablets in healthy adult subjects, and to identify the metabolites of HSK7653 in healthy adult subjects

NCT ID: NCT05943886 Completed - Obesity Clinical Trials

A Phase 1 Study of HEC88473 Injection in Healthy Subjects, Obese Subjects and T2DM Subjects

Start date: August 11, 2021
Phase: Phase 1
Study type: Interventional

This is a single-center, randomized, double-blind, placebo-controlled, escalating single-dose and multiple-dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HEC88473 injection in healthy subjects, obese subjects and subjects with type 2 diabetes mellitus (T2DM).

NCT ID: NCT05376969 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Evaluate the Long Term Safety and Efficacy of DWP16001 add-on to Metformin in Patients With T2DM Inadequately Controlled on Metformin

ENHANCE-MEXT
Start date: May 25, 2021
Phase: Phase 3
Study type: Interventional

A Multi-center, Open-label, Extension study to Evaluate the long term Safety and Efficacy of DWP16001 add-on to metformin in Patients with type 2 diabetes mellitus inadequately controlled on metformin

NCT ID: NCT05376930 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Study to Evaluate the Long Term Safety and Efficacy of DWP16001 Compared to Placebo in the Treatment of T2DM.

Start date: September 16, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is evaluate the long term safety and efficacy of DWP16001 compared to placebo in the treatment of type 2 diabetes mellitus.

NCT ID: NCT05279911 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Effect of Low-level Laser Therapy on Type II Controlled Diabetic Patients After Dental Implant Insertion

Start date: March 3, 2021
Phase: N/A
Study type: Interventional

This study aimed therefore to evaluate bone density (BD) and OPG levels in the peri-implant crevicular fluid (PICF) in lased controlled type II Diabetes Mellitus (T2DM) patients versus non-lased T2DM patients. 40 T2DM patients were included in this study. Implants were randomly inserted in 20 non-lased T2DM patients (Control) and 20 lased T2DM patients (Intervention). BD and OPG levels in the PICF were assessed in both groups at the follow up points.

NCT ID: NCT04970940 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

The Drug-drug Interaction Study of AJU-A51R1 and AJU-A51R2

Start date: July 2, 2020
Phase: Phase 1
Study type: Interventional

To evaluate a pharmacokinetic drug interaction between AJU-A51R1 and AJU-A51R2 in healthy male volunteers.

NCT ID: NCT04688359 Completed - Clinical trials for Cardiovascular Risk Factor

Effectiveness of Nurse-coordinated Follow-up Program in Primary Care for People at Risk for T2DM

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Previous Icelandic studies regarding prevalence of diabetes have mostly used data from the capital area. Information on the proportion of people at risk at developing T2DM or having undiagnosed T2DM among people living in rural Northern Iceland is unknown. Clinical guidelines recommend that patients with prediabetes (diabetes warning signs) should be referred to a counselling program. The study will evaluate effectiveness of nurse-coordinated Guided Self-Determination (GSD) follow up program toward health promotion, for people at risk of T2DM.

NCT ID: NCT04654390 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

The Efficacy Nad Safety of DWP16001 Compared to Active Drug in the Treatment of Type 2 Diabetes Mellitus

Start date: December 30, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of DWP16001 compared to active drug in the treatment of type 2 diabetes mellitus.

NCT ID: NCT04634500 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

The Efficacy and Safety of DWP16001 in Combination With Metformin in Patients With Type 2 Diabetes.

ENHANCE-M
Start date: November 18, 2020
Phase: Phase 3
Study type: Interventional

Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of DWP16001 in Combination with Metformin in Patients With Type 2 Diabetes Mellitus who Have Inadequate Glycemic Control on Metformin Alone.