Systemic Sclerosis Clinical Trial
Official title:
Systemic Sclerosis Cohort in Seoul National University Hospital Single Center Prospective Cohort, of Patients With Systemic Sclerosis in Korea
To establish a new prospective cohort of Korean patients with systemic sclerosis and track
the natural history of the disease over time.
To generate new hypotheses for further investigation.
Systemic sclerosis (SSc) is a multisystem and heterogeneous disease characterized by an
unpredictable course and high morbidity and mortality. The complexity of SSc requires
interdisciplinary diagnostic and therapeutic management and result in a growing burden for
all health-care systems. For this reasons, researchers are seeking new diagnostic and
therapeutic strategies to improve management of these patients. In order to improve clinical
care and to develop recommendations for the diagnosis and treatment of SSc, disease
registries are used to capture and track key patient information.
Therefore, SSc research associations and consortiums play a pivotal role to perform ongoing
research and data collection to understanding the disease and support research projects.
Currently, several national SSc registries in the UK, Germany, USA, Canada, Brazil,
Australia and international registry, EUSTAR (European League Against Rheumatism scleroderma
trial and research), have been established. However, the natural history of Asian
populations are fully evaluated. Therefore, investigators decided to establish SSc cohort in
Korean patients.
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Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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|
Phase 1/Phase 2 | |
| Completed |
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|
Phase 2 | |
| Recruiting |
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RY_SW01 Cell Injection Therapy in Systemic Sclerosis
|
Phase 1/Phase 2 | |
| Recruiting |
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Subcutaneous Injections of ASC to Heal Digital Ulcers in Patients With Scleroderma.
|
Phase 2 | |
| Suspended |
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|
Phase 2 | |
| Not yet recruiting |
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Manufacturing of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells for Treatment of Severe Systemic Sclerosis
|
N/A | |
| Not yet recruiting |
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Sirtuin 3 and Sirtuin 7 in Systemic Sclerosis
|
N/A | |
| Not yet recruiting |
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Efficacy of a Personalized Rehabilitation Program of Facial Involvement in Systemic Sclerosis
|
N/A | |
| Recruiting |
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CSL Behring Sclero XIII
|
Phase 2 | |
| Terminated |
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Evaluating Lung Doppler Signals in Patients With Systemic Sclerosis (SSc)
|
N/A | |
| Terminated |
NCT02243111 -
Detecting Pulmonary Arterial Hypertension (PAH) in Patients With Systemic Sclerosis (SSc) by Ultrasound
|
N/A | |
| Completed |
NCT01933334 -
Safety and Tolerability of Pirfenidone in Patients With Systemic SclerosisâRelated Interstitial Lung Disease (SSc-ILD) (LOTUSS)
|
Phase 2 | |
| Completed |
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Hemodynamic Changes in Connective Tissue Disease
|
N/A | |
| Terminated |
NCT00848107 -
Open-Label Study of Oral Treprostinil in Digital Ulcers
|
Phase 2 | |
| Completed |
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Effect of Rosuvastatin on Systemic Sclerosis-related Pulmonary Hypertension
|
Phase 3 | |
| Completed |
NCT00074568 -
Scleroderma Registry
|
||
| Not yet recruiting |
NCT06412614 -
Evaluation of Patients With Systemic Sclerosis Without Specific or Associated Autoantibodies
|
||
| Terminated |
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Effect of Different Iloprost Doses on Symptoms in Systemic Sclerosis
|
Phase 2 | |
| Recruiting |
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Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis
|
Phase 4 | |
| Recruiting |
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|
N/A |