Systemic Sclerosis Clinical Trial
Official title:
Prevention and Treatment of Interstitial Lung Disease in Systemic Sclerosis
Systemic sclerosis (SSc) is an orphan, multiorgan disease affecting the connective tissue of
the skin and all internal organs. Interstitial lung disease is a frequent morbidity and
mortality-driving manifestation in systemic sclerosis.
This observational trial (OT) is part of the collaborative project "DeSScipher", one out of
five OTs to decipher the optimal management of systemic sclerosis. Aim of this observational
try is to identify:
- The state of clinical practice in Europe for prevention and treatment of interstitial
lung disease and its impact on lung function and disease progression
- The potential predictors and confounders for response to therapy
Patients are routinely evaluated every 3 months over a 12-months period by medical history, physical examination, pulmonary function tests, VAS lung score and SF-36, SHAQ. Also, their medication and possible medication changes will be recorded. ;
Observational Model: Cohort, Time Perspective: Prospective
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