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Non-Invasive Diagnostic and Functional Evaluation of Cardiac Involvement in Patients With Systemic Sclerosis

Systemic Sclerosis Clinical Trial

Clinical Trial Summary

The aim of this study was to assess serum N-terminal proBNP (NT-proBNP) in systemic sclerosis patients and to establish whether it reflects the severity of RV overload.

Clinical Trial Description

Elevated serum brain natriuretic peptide (BNP) levels released from myocytes of ventricles upon stretch have been found in patients with isolated right ventricular (RV) pressure overload. However, limited data suggest that serum BNP may be elevated in patients with systemic sclerosis (SSc), especially with RV dysfunction. The aim of this study was to assess serum N-terminal proBNP (NT-proBNP) in SSc patients and to establish whether it reflects the severity of RV overload. ;

Study Design

Observational Model: Defined Population, Primary Purpose: Screening, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00453752
Study type Observational
Source Medical University of Warsaw
Contact Ciurzynski Michal, M.D, Ph.D
Phone +48 22 502 11 44
Email mciurzyn@amwaw.edu.pl
Status Recruiting
Phase N/A
Start date April 2006
Completion date April 2010
View Details
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