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Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-year Manometric Follow-up

Systemic Sclerosis Clinical Trial

Official title:
Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-year Manometric Follow-up

Clinical Trial Summary

Small bowel involvement is still recognized to be associated with great morbidity and mortality in SSc patients, leading particularly to malabsorption and intestinal pseudo-obstruction. Intestinal disorders directly related to SSc have, in fact, been reported to be one of the most common causes of death.

In a previous prospective study, we have demonstrated the high prevalence of small intestinal involvement in SSc patients, using upper intestinal manometry; in turn, 88% of our SSc patients had upper intestinal motor disturbances. However, to date, no authors have yet analyzed the course of upper intestinal motor dysfunction in SSc.

The aims of this study were therefore to assess the 5-year course of small bowel motor disorders, using manometry in patients with systemic sclerosis (SSc), and to investigate for an association between upper intestinal motor dysfunction outcome and other clinical manifestations of SSc.

Clinical Trial Description

n/a

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00213460
Study type Observational
Source University Hospital, Rouen
Contact
Status Completed
Phase N/A
Start date August 2001
Completion date July 2003
View Details
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