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Studying Complement Inhibition in Complex Cardiac Surgery — CARDIAC  

Systemic Inflammatory Response Syndrome Clinical Trial

Official title:
A Phase II Randomized, Placebo-controlled, Double-blind, Dose-escalation Study to Evaluate Safety, Pharmacokinetics and Pharmacodynamic Dose Response Relationship of IFX-1 in Patients Undergoing Complex Cardiac Surgery

Clinical Trial Summary

The trial enrolls patients undergoing a complex cardiac surgery. The primary goal of the trial is to evaluate the pharmacodynamic dose response relationship of the monoclonal antibody IFX-1 in these patients. In addition, this trial further aims to characterize the safety and the pharmacokinetics of IFX-1 as well as to collect first data on its efficacy on clinical surrogate endpoints.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02866825
Study type Interventional
Source InflaRx GmbH
Contact
Status Completed
Phase Phase 2
Start date May 2016
Completion date January 2017
View Details
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