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Syndrome clinical trials

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NCT ID: NCT06298864 Recruiting - Clinical trials for Acute Coronary Syndrome

Internet-based Behavioral Intervention Following ACS

ACS-CBT
Start date: March 10, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate if an online Cognitive Behavioral Therapy (CBT) protocol customized for patients following Acute Coronary Syndrome (ACS), reduce cardiac anxiety, enhance Quality of Life (QoL), and promote increased physical activity while controlling for caregiver attention, utilizing an active control group receiving internet-based cardiac lifestyle intervention.

NCT ID: NCT06298643 Active, not recruiting - Clinical trials for Lower-risk Myelodysplastic Syndromes

Real-World Practice Patterns and Outcomes of Lower-Risk Myelodysplastic Syndrome Patients in Japan

Start date: December 22, 2023
Phase:
Study type: Observational

The purpose of this study is to describe the treatment patterns, clinical outcomes, healthcare resource utilization (HCRU) and medical costs of lower-risk myelodysplastic syndromes patients in Japan.

NCT ID: NCT06297941 Recruiting - Clinical trials for Acute Myeloid Leukemia

Study of REM-422 in Patients With AML or Higher Risk MDS

Start date: April 26, 2024
Phase: Phase 1
Study type: Interventional

The goal of this study is to determine the safety and antitumor effects of REM-422, a MYB mRNA degrader, in people with Higher Risk MDS and relapsed/refractory AML

NCT ID: NCT06297785 Recruiting - Clinical trials for IBS - Irritable Bowel Syndrome

Online, Gut-directed Hypnotherapy for Patients With Irritable Bowel Syndrome (IBS)

Start date: October 17, 2022
Phase: N/A
Study type: Interventional

Adult IBS patients with symptoms refractory to standard medical treatment will receive online nurse-administered, gut-directed hypnotherapy in groups. The primary outcome measure was change in gastro-intestinal symptom severity.

NCT ID: NCT06297421 Not yet recruiting - Mental Health Issue Clinical Trials

Efficacy and Safety of FMT for the Treatment of IBS-D and Mental Health Comorbidity in Young Adults

Start date: August 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Fecal Microbiota Transplantation compared with placebo in the treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D) and Mental Health Comorbidity in Young Adults.

NCT ID: NCT06297213 Not yet recruiting - Sjogren's Syndrome Clinical Trials

R-2487 in Patients With Sjogren's Syndrome (SS)

R-2487-SS-01
Start date: June 1, 2024
Phase: Phase 1
Study type: Interventional

The goal of this study is to determine the safety and tolerability of orally taken probiotic (R-2487) in patients with Sjogren's Syndrome. Patients will take an oral dosage of probiotic (R-2487) and physicians will assess and measure their Sjogren's Syndrome. Blood and fecal evaluations of inflammation and assessment of probiotic (R-2487) on fecal level will also be measured.

NCT ID: NCT06297148 Recruiting - Clinical trials for Trochanteric Bursitis

The HIP Self-management Study

HIPS
Start date: March 12, 2024
Phase: N/A
Study type: Interventional

The HIPS-study will be an observer blinded, single-centre, parallel-group randomized controlled trial (RCT). The main purpose of the study is: 1. To investigate the clinical effectiveness of a self- management program versus usual care for patients with greater trochanteric pain syndrome (GTPS). - H0: There is no difference between a self-management program and usual care on pain and function in patients with GTPS. - H1: There is a difference between a self-management program and usual care on pain and function in patients with GTPS. 2. To investigate if self-management is more cost-effective than usual care in the treatment of patients with GTPS. Participants will be randomly allocated into one of two groups: 1) self-management program or 2) usual care. Follow-up will be at 3-, 6- and 12-months.

NCT ID: NCT06296914 Recruiting - Clinical trials for POTS - Postural Orthostatic Tachycardia Syndrome

A mHealth System for Patients With POTS

Start date: February 20, 2024
Phase: N/A
Study type: Interventional

Postural Orthostatic Tachycardia Syndrome (POTS) affects approximately 500,000 - 3 million Americans. This number will only increase due to the large number of patients experiencing POTS due to "long COVID." POTS patients experience several symptoms, including tachycardia, palpitations, dizziness, and pre-syncope or syncope, among others. POTS can be very debilitating and not only affect patients physically but also emotionally and financially. It takes an average of four years and seven doctors for POTS patients to achieve a diagnosis and it is often a frustrating and negative experience fraught with misdiagnoses, stigma, and depression and anxiety. Recent research demonstrates that mHealth technology may be one way that POTS patients can improve their experience in the healthcare system by providing objective data to their healthcare providers. Patients may also better take care of themselves through symptom monitoring and instant patient education via mHealth technology. The two study aims are: 1) Developing a mHealth app to improve the delay to diagnosis and the quality of life of POTS patients; and 2) Evaluate the usability and feasibility of the mHealth app and study design. To achieve these aims, researchers in this study will work with a programmer and leaders from the mHealth Application Modernization and Mobilization Alliance (MAMMA) and stakeholders (patients, caregivers, and providers) to co-design a mHealth app for POTS patients, including key educational components guided by the IDEA model, an instructional risk communication approach. A group of diagnosis-seeking POTS (n=20) patients will pilot test the app and provide feedback for improvement as well as evaluate its usability. Results from this study will allow researchers to acquire necessary data to apply for external funding to conduct a larger clinical trial to evaluate its influence on health outcomes, such as patient experience during visits with physicians, perceived stigma, and time to diagnosis.

NCT ID: NCT06296043 Recruiting - Clinical trials for Premenstrual Syndrome

The Effect of Su-Jok Application and Progressive Muscle Relaxation Exercises in Coping With Premenstrual Syndrome

Start date: April 10, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effect of su-jok application and progressive muscle relaxation exercise in coping with premenstrual syndrome.

NCT ID: NCT06295315 Recruiting - Clinical trials for Prader-Willi Syndrome

Evaluation of the Psychological Profile of Adult Patients With Prader-Willi Syndrome

PROPSICOPWS
Start date: April 21, 2023
Phase:
Study type: Observational

The primary aim of the present study is to investigate the psychological profile of adult patients with PWS and the fatigue experienced by family members. Specifically, the level of psychological well-being, the subjective perception of life quality, and the main characteristics present in terms of psychopathological functioning of subjects with PWS will be investigated. These variables will be investigated in order to detect their presence and the main bonds of interaction, either between them or with other socio-demographic data, in a sample of adults with PWS. At the same time, the presence of psychological distress, levels of well-being quality of life, and coping strategies in family members and caregivers of individuals with PWS will be investigated.