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Syndrome clinical trials

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NCT ID: NCT06365801 Not yet recruiting - Clinical trials for Irritable Bowel Syndrome

Investigation of Acupoint in Irritable Bowel Syndrome Based on Biological Characteristics

Start date: April 2024
Phase:
Study type: Observational

Irritable bowel syndrome (IBS) is a common functional disorder of the digestive system characterized by recurrent abdominal pain associated with bowel movements or changes in bowel habits. Although there are reviews and guidelines for treating IBS, the complexity and diversity of IBS manifestations make treatment difficult. By detecting and exploring the biological characteristics presented by the relevant meridian point reaction, this project clarified the specificity and regularity of the connection between the acupoint and the Zangfu reflected by this phenomenon, and conducted correlation analysis based on the intestinal flora, tryptophan metabolite levels and related scales of patients with IBS.

NCT ID: NCT06363955 Completed - Postoperative Pain Clinical Trials

Assessing the Efficacy of a Hydrogen Peroxide Mouthwash for Oral Wound Healing, Oral Hygiene and Xerostomia Relief

Start date: April 25, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety of a hydrogen carbamide/peroxide mouthwash, named UNISEPT® MOUTHWASH, regarding oral wound healing, postoperative symptoms, xerostomia (dry mouth) and oral hygiene improvement. Study participants have reported dry mouth and are scheduled for a diagnostic biopsy of minor labial salivary glands to investigate Sjögren's Syndrome, following consultation with their rheumatologist. This is a standardized diagnostic procedure that leads to healing by primary intention (i.e. wound edges are closely re-approximated with sutures). Researchers are comparing this mouthwash with a placebo (a look-and-taste-alike substance that contains no active ingredients) to see if it is helpful with healing of wounds in the mouth and associated symptoms, improving dry mouth and/or oral hygiene. Participants randomly get the hydrogen carbamide/peroxide mouthwash or the placebo one to use for 14 days after the biopsy. The investigators will not know which one they are providing as the bottles will be identical. Oral wound healing, postoperative symptoms (such as pain, eating and speech difficulties), oral hygiene (dental plaque and gingival inflammation), improvement of dry mouth and quality of life are assessed during a 14-day period after the biopsy. Participants are required to visit the clinic three times, one for the initial consultation and the biopsy, one at 7 days and one at 14 days after the biopsy. They are asked to fill in some questionnaires, while certain procedures (such as measuring saliva) and assessments (like evaluating the dental plaque and gingival inflammation) take place. During the first week they, also, keep a diary of their symptoms, as instructed.

NCT ID: NCT06363864 Not yet recruiting - Metabolic Syndrome Clinical Trials

Investigation of Metabolomics Differences Between Metabolic Syndrome and Healthy Individuals in Taiwan

Start date: April 14, 2024
Phase:
Study type: Observational

The prevalence of metabolic syndrome in Taiwan has been increasing yearly. In this project, the database of blood test results from healthy and metabolic syndromes individuals will be analyzed to identify the small molecules related to the severity of metabolic syndrome. These identified small molecules could be used as biomarkers to predict the development of metabolic syndromes in the future.

NCT ID: NCT06361004 Not yet recruiting - Tourette's Syndrome Clinical Trials

Exploring DBS Efficacy in Treatment-refractory Tourette's Syndrome

Start date: April 20, 2024
Phase: N/A
Study type: Interventional

The primary purpose of this study is to investigate the effect of deep brain stimulation (DBS) in patients with Treatment-refractory Tourette's syndrome (TR-TS) implantation targeting the Antero-medial globus pallidus interna (GPi), Antero-medial globus pallidus interna (amGPi), Postero-ventrolateral GPi (pvGPi), Centromedian nucleus, substantia periventricularis and nucleus ventro-oralis internus (Cm-Spv-Voi), Centre median nucleus and nucleus ventro-oralis (Cm-Voi), or Nucleus Accumbens/ Anterior Limb of Internal Capsule (NA-ALIC), or other unreported nuclei targets.

NCT ID: NCT06360510 Active, not recruiting - Clinical trials for Carpal Tunnel Syndrome

Comparison of %5 Dextrose and Betamethasone Injections in Patients With Carpal Tunnel Syndrome

Start date: May 5, 2023
Phase:
Study type: Observational

The aim of the study is to compare the effectiveness of ultrasound-guided betamethasone and 5% dextrose injection, which is routinely applied in clinical practice, in patients with mild and moderate carpal tunnel syndrome (CTS).

NCT ID: NCT06360237 Available - Clinical trials for Familial Chylomicronemia Syndrome

Olezarsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Start date: n/a
Phase:
Study type: Expanded Access

The purpose of the Expanded Access Program is to provide pre-approval access of olezarsen to eligible patients with Familial Chylomicronemia Syndrome (FCS).

NCT ID: NCT06359561 Enrolling by invitation - Clinical trials for Chronic Pain Syndrome

Assessment of Effectiveness and Stimulation Coverage of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Patients With Cervical Lead Placement

Start date: October 5, 2023
Phase:
Study type: Observational

This observational, prospective data collection is designed to evaluate the effectiveness and stimulation coverage of closed-loop spinal cord stimulation (CL-SCS) therapy in patients with cervical lead placement.

NCT ID: NCT06358326 Recruiting - Clinical trials for Carpal Tunnel Syndrome

Dry Needling and Rehabilitatin Carpal Tunnel Syndrome

Start date: April 5, 2024
Phase: N/A
Study type: Interventional

Dry needling is used for myofascial release. However, its effectiveness in carpal tunnel syndrome (CTS) is not well known. It is thought that dry needling may also be an effective treatment for CTS by providing relaxation in the fascial tissue. Therefore, this study will examine the effects of dry needling treatment on pain, function, range of motion, proprioception and disability in patients with CTS.

NCT ID: NCT06358300 Completed - Clinical trials for Polycystic Ovary Syndrome

Visceral Adiposity Index Differences Between Subtypes of Polycystic Ovary Syndrome

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

We aimed to investigate visceral adiposity index (VAI) in patients with different phenotype of policystic ovary syndrome (PCOS) and to compare healthy controls.

NCT ID: NCT06355882 Recruiting - Clinical trials for Low Cardiac Output Syndrome

Patients With Low Cardiac Output Syndrome Undergoing Local Dental Anesthesia

Start date: August 8, 2023
Phase: N/A
Study type: Interventional

Patients with low cardiac output syndrome requiring surgical and periodontal dental treatment will be selected to undergo the dental procedure using local dental anesthetic: 2% lidocaine with epinephrine and 2% lidocaine without vasoconstrictor. Cardiovascular events and the safety of using two cartridges (3.6 mL) will be evaluated. They will be evaluated by Holter monitoring in the period of 1 hour before, during and 1 hour after the procedure and blood pressure correction will be performed