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Clinical Trial Summary

The aim of the study is to compare the anesthetic efficacy and need for supplemental anesthesia of 1.8 ml compared to 3.6 ml of 4% articaine buccal infiltration in mandibular molars with symptomatic irreversible pulpitis.


Clinical Trial Description

Patients with moderate-to-severe pain due to symptomatic irreversible pulpitis will be included. Patients will be randomly assigned into two groups to receive either 1.8 ml 4% articaine buccal infiltration or 3.6. ml 4% articaine buccal infiltration before single visit root canal treatments. Intraoperative pain will be assessed using an 11-point numerical rating scale (NRS) so that anesthetic success will be defined as no to mild intraoperative pain. The need for supplemental anesthesia will also be recorded. ;


Study Design


Related Conditions & MeSH terms

  • Pulpitis
  • Symptomatic Irreversible Pulpitis

NCT number NCT06119139
Study type Interventional
Source Cairo University
Contact Hebatullah Moheb Ibrahim
Phone 00201114563058
Email heba.eid@dentistry.cu.edu.eg
Status Not yet recruiting
Phase N/A
Start date December 2023
Completion date June 2025

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