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Surgical Wound clinical trials

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NCT ID: NCT03317184 Recruiting - Donor Nephrectomy Clinical Trials

Hand-assisted Laparoscopic Donor Nephrectomy Periumbilical Versus Pfannenstiel Incision

HAPERPACT
Start date: November 1, 2017
Phase: N/A
Study type: Interventional

Despite efforts to optimize the transplantation of deceased donor kidneys, the number of available kidneys continues to fall short of the demand. Living donor kidneys have been used to overcome this shortage. Graft and patient survival is significantly higher following living donor kidney transplantation compared with deceased donor kidney transplantation. Open donor nephrectomy was the universal technique prior to the advent of laparoscopic techniques. Laparoscopic approaches have definite advantages over open surgery in terms of blood loss, postoperative pain, analgesic requirements, duration of hospital stay, and convalescence. There is some controversy regarding longer warm ischemia time, longer operative time, and increased bleeding with laparoscopic nephrectomy compared with hand-assisted laparoscopic living donor nephrectomy (HALDN). HALDN attempted to reduce warm ischemia time by using the hand port to extract the kidney instantly after dividing the blood vessels. This technique also offers tactile feedback, better manual control of bleeding, a relatively shorter learning curve, less kidney traction, faster kidney removal, and shorter warm ischemic periods. HALDN is often performed using periumbilical and Pfannenstiel incisions for hand-assisted port placement. Pfannenstiel incisions improve wound complications such as incisional hernia, cosmetic issues, and wound dehiscence. However, duration of surgery, postoperative pain score, and length of hospital stay are significantly lower in donors with periumbilical incisions.To the best of our knowledge, these two types of incision have not been compared in a randomized controlled trial in patients undergoing HALDN. Our objective is to compare the results of Pfannenstiel incision (intervention group) with periumbilical incision (control group). The return to normal physical activity will be evaluated in a clinical randomized trial using an expertise-based design.

NCT ID: NCT03303027 Completed - Clinical trials for Surgical Wound Cosmesis

6-0 Fast Absorbing Gut Versus 5-0 Fast Absorbing Gut for Linear Wound Closure

Start date: April 27, 2016
Phase: N/A
Study type: Interventional

Traditionally, dermatologic surgeons close wounds with stitches. Fast absorbing gut is a dissolvable stitch that is very commonly used. Some surgeons believe that using a thinner size of this stitch causes less skin reaction and improves the cosmetic outcome of the scar. Other surgeons believe that using a thicker size of this stitch reduces the tension on the scar and improves the cosmetic outcome of the scar in that manner. The investigator wishes to determine whether the thickness of the fast absorbing gut suture that is used makes a difference in the cosmetic outcome of the scar.

NCT ID: NCT03302988 Completed - Operative Wound Clinical Trials

Wound Eversion Versus Planar Closure for Face or Neck Wounds

Start date: October 13, 2015
Phase: N/A
Study type: Interventional

The aim of this study is to determine whether wound edge eversion, achieved by careful placement of dermal sutures, improves the cosmetic outcome of operative wounds closed on the head or neck.

NCT ID: NCT03293862 Completed - Clinical trials for Surgical Wound Dehiscence

Prevention of Fascial Dehiscence With Prophylactic Onlay Mesh in Emergency Laparotomies

Start date: June 2015
Phase: N/A
Study type: Interventional

Facial dehiscence elicit high morbidity and mortality. This complication may arise in more than 8.5% of high-risk patients. Addressing risk factors and optimizing surgical technique are guarded as mainstay measures for prevention, but their efficacy is questionable. The aim of this study is to analyze the influence of using a polypropylene onlay prophylactic mesh on the incidence of fascial dehiscence in emergency surgery and associated complications.

NCT ID: NCT03286452 Completed - Pressure Ulcer Clinical Trials

The RESPOND Registry

RESPOND
Start date: February 21, 2017
Phase:
Study type: Observational [Patient Registry]

The RESPOND Registry is an observational study to assess the impact of PuraPly™ AM on the management of wounds in real world clinical settings; no experimental intervention is involved.

NCT ID: NCT03274466 Completed - Clinical trials for Postoperative Complications

Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty

PROMISES
Start date: December 5, 2017
Phase: N/A
Study type: Interventional

This study evaluates surgical site complications in subjects undergoing revision of a total knee arthroplasty when closed incision negative pressure therapy is used to manage the closed incision, as compared to a standard of care dressing.

NCT ID: NCT03273777 Recruiting - Cesarean Section Clinical Trials

Skin Incision Skewness at Cesarean Section

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Skin incision skewness, incision length on both sides of the midline and patient's perception of the scar after cesarean section will be compared between the following two groups: (1) Drawing of an incision line prior to skin incision and (2) no drawing of an incision line.

NCT ID: NCT03271164 Completed - Clinical trials for Post-surgical Wounds

Evaluation of the Safety and Efficacy of FBPM10 System in the Treatment of Post-surgical Wounds

Start date: August 29, 2017
Phase: N/A
Study type: Interventional

This is a prospective randomized controlled case series in patients having a surgery for bilateral breast reduction. Objectives of the case series are to evaluate the safety and efficacy of the FBPM10 System when compared with standard of care (massages with vitamin E cream) in the treatment of post-surgical wounds.

NCT ID: NCT03261830 Completed - Clinical trials for Supracondylar Humerus Fracture

Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)

Start date: August 18, 2017
Phase: Phase 4
Study type: Interventional

The aim of this study is to determine if antibiotics affect the outcome after percutaneous surgery for pediatric supracondylar humerus fractures. The patient population will be recruited from the cohort presenting to Women and Children's Hospital for percutaneous fixation of pediatric supracondylar humerus fractures who meet the eligibility criteria and consent to taking part in the study. Patients will be followed up for 3-6 weeks depending on age, and will be evaluated on the presence or absence superficial or deep infection, Visual Analog Scale pain scores, time to healing, need for repeat casting, and loss of fixation.

NCT ID: NCT03250442 Recruiting - Amputation Clinical Trials

Evaluating the Outcomes for Incisional Application of Negative Pressure for Nontraumatic Amputations

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate how well subjects heal after surgery who receive standard dressings or incisional negative pressure wound therapy for non-traumatic amputation sites.