Ultrasound to Prevent Leg Wound Complications in Heart Bypass.

Status Terminated

Clinical Trial Summary

The long saphenous vein is traditionally harvested for use as a conduit in coronary artery bypass grafting surgery. Currently, the long saphenous vein is not imaged prior to surgery. This study aims to evaluate preoperative ultrasound mapping of the long saphenous vein to to improve patient and clinical outcomes.

Clinical Trial Description

A vein from the leg is widely is widely harvested during coronary artery bypass grafting (CABG) surgery for bypass of diseased coronary arteries. This vein is called the long saphenous vein.

Currently, the long saphenous vein (LSV) is harvested blind by surgical practitioners with no imaging prior to surgery to decide on whether this vein is suitable for use in heart bypass surgery. This can result in fruitless incisions and result in additional unnecessary surgical wounds in the leg(s) to identify a suitable section of vein that can be used in the bypass operation. In these cases, excessive surgical trauma to the leg can increase the risk of a wound infection.

There is some evidence that ultrasound imaging of the LSV improves leg wound outcomes in patients having CABG surgery. Some studies have reported reductions in vein wound infection rates, vein harvest time, length of hospitalisation and length of wounds.

The purpose of this study will be to investigate the potential benefit of ultrasound imaging as a randomised control trial. One group will have ultrasound imaging of the long saphenous vein prior to heart bypass surgery. A second group will not undergo ultrasound imaging which is current practice at the Bristol Heart Institute.

Ultrasound imaging of the long saphenous vein will allow planning and selection of the most optimal segment of vein. This targeted approach will allow guidance of surgical incisions away from unsuitable segments and thus potentially improving leg wound outcomes.

The primary endpoint for this study will be to assess leg wound infection between the two randomised groups. Other endpoints that will be assessed are patient satisfaction, wound length, time taken to remove the vein, blood loss from the leg wound during surgery and the number of wounds in your leg. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02307084
Study type	Interventional
Source	University Hospitals Bristol NHS Foundation Trust
Contact
Status	Terminated
Phase	N/A
Start date	February 2015
Completion date	February 13, 2017

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05529173` - Povidone-Iodine for Nasal Decolonization	Phase 4
Recruiting	`NCT03295955` - Comparing Efficacy of Postoperative Oral Antibiotic Use in Trans-Oral Thyroidectomy	N/A
Not yet recruiting	`NCT05276687` - Efficacy of Diluted Betadine vs Antibiotic Installation Before Surgical Wound Closure in Prevention of Post Cardiac Surgery Wound Infection	Phase 4
Completed	`NCT02776774` - Topical Antibiotic Treatment for Spine Surgical Site Infection
Terminated	`NCT00386477` - Vaginal Cleansing at Cesarean Delivery to Reduce Infection: A Randomized, Controlled Trial	N/A
Not yet recruiting	`NCT03872544` - Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
Recruiting	`NCT05077592` - Addition of Pre-wound Closure Povidone Iodine Wash Versus Direct Wound Closure Effect on Surgical Site Infections	Phase 4
Completed	`NCT03148067` - Incidence and Risk Factors for Surgical Site Infection After Intramedullary Nailing of Femoral and Tibial Fractures
Enrolling by invitation	`NCT03880188` - Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
Completed	`NCT01890720` - Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following Caesarean Section	N/A
Recruiting	`NCT06319235` - Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG®	Phase 1/Phase 2
Completed	`NCT02919410` - Bacterial Colonization With and Without Iodophor-impregnated Adhesive Drapes in Hip Surgery: a Prospective, Randomized Trial	N/A
Completed	`NCT02020018` - Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection	N/A
Completed	`NCT01741649` - Clorhexidine Versus Povidone for the Prevention of Surgical Site Infection After Cesarean Section	N/A
Completed	`NCT01340534` - Supplemental Perioperative Oxygen to Reduce the Incidence of Post-cesarean Wound Infection	Phase 3
Not yet recruiting	`NCT01457859` - Effectiveness of Triclosan Coated Sutures in Preventing Leg Wound Infection After Coronary Artery Bypass Surgery	Phase 4
Completed	`NCT03365219` - Alexis O-Ring Wound Retractor for the Prevention of Post-cesarean Surgical Site Infections	N/A
Completed	`NCT01026259` - Local Warming of Surgical Incisions	Phase 3
Completed	`NCT03574090` - Study the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Infection in Colorectal Surgery	Phase 4
Completed	`NCT03199911` - Topical Antibiotic Prophylaxis for Eyelids	Phase 4