Surgical Site Infection Clinical Trial
Official title:
Effect of Intraperitoneal Irrigation With Antibiotic Solution, Triclosan-impregnated Sutures for Fascial Closure and Mupirocin Ointment Over the Skin Staples, on Surgical-site Infection After Laparoscopic Colorectal Surgery
A prospective randomized clinical trial will be performed. Patients will be randomized in 2
groups. The experimental group will undergo the combined application of intraperitoneal
irrigation with clindamycin and gentamicin solution, fascial closure with
Triclosan-impregnated sutures and application of mupirocin ointment over the skin staples,
in addition to the standard care measures. The control group undergo only the standard care
measures.
Incisional surgical-site infection will be investigated.
A prospective randomized clinical trial will be performed. Patients will be randomized in 2
groups. The experimental group will undergo the combined application of intraperitoneal
irrigation with clindamycin (600mg) and gentamicin (240 mg) solution in 250 ml of normal
saline, fascial closure with Triclosan-impregnated polyglactin suture and application of
mupirocin ointment over the skin staples, in addition to the standard care measures. The
control group undergo only the standard care measures, including decontamination of the skin
during surgery with chlorhexidine alcohol solution, administration of systemic antibiotic
prophylaxis and application of thermal blanket to avoid hypothermia. In the control group,
the fascial closure will be performed with a polyglactin suture (without Triclosan
impregnation).
Incisional surgical-site infection will be investigated.
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