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Surgical Site Infection clinical trials

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NCT ID: NCT01697748 Completed - Post Operative Pain Clinical Trials

Prospective Study on Cesarean Wound Outcomes

Start date: September 2013
Phase: N/A
Study type: Interventional

This study will investigate whether the placement of silver impregnated dressings beginning in the OR will improve wound healing in patients undergoing cesarean delivery compared to traditional Telfa pads. This study will also explore the presumed improvement in scar integrity when silver impregnated dressings are used compared to the Telfa pads. The study will compare the percentage of patients who develop a surgical site infection after application of silver impregnated dressings versus standard Telfa dressings. Investigators will also assess the cosmetic appearance and pain of the cesarean section scar at the patient's one week and 6 week post-operative visits.

NCT ID: NCT01679379 Completed - Clinical trials for Surgical Site Infection

Wound Infection in Obese Women After Cesarean Delivery

Start date: July 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the surgical site infection rate and patient satisfaction for absorbable versus non absorbable suture in closure of skin at cesarean section in obese women.

NCT ID: NCT01659983 Completed - Clinical trials for Surgical Site Infection

Efficacy Study of Delayed Primary Closure to Reduce Rate of Wound Infection in Complicated Appendicitis

Start date: November 2012
Phase: Phase 3
Study type: Interventional

Research hypothesis: Does delayed primary wound closure after appendectomy in adults with complicated appendicitis reduce postoperative superficial surgical site infection compare to primary wound closure. Study design: This study is a multicenter randomized controlled trial of delay versus primary wound closure in complicated appendicitis. Setting: Thammasat Hospital, Ramathibodi Hospital, Chonburi Hospital, Chonpratarn Hospital, Vachira Hospital, and Pathumthani Hospital Participants: Adult patients age 18 years or older and non-pregnant in women who have been diagnosed as gangrenous or ruptured appendicitis. Outcome: Superficial surgical site infection Period of study: August 2012 - August 2014

NCT ID: NCT01648088 Completed - Clinical trials for Surgical Site Infection

Detection of Staph Colonization in Pre-op Arthroplasty Patients

Staph
Start date: September 1, 2012
Phase:
Study type: Observational

This study will evaluate which body site(s) provide the best source of possible staph presence in participants undergoing total joint arthroplasty. If the pre-operative cultures indicate staph presence, an Infectious Disease specialist will be consulted for standard of medical care consultation and treatment management. Participants will be followed for 2 years post-implantation of prosthetic joint to monitor development of prosthetic joint infection.

NCT ID: NCT01610271 Completed - Clinical trials for Surgical Site Infection

Air Barrier System for the Prevention of Surgical Site Infection

ABS
Start date: January 2012
Phase: N/A
Study type: Interventional

Airborne particles are present in all indoor environments including the operating room. Most of these particles come from the surgical staff moving around in the room, positioning of the patient during surgery, and the movement of surgical equipment and supplies. While the amount of particulate in an operating room is much, much less than is found in a typical home or public space, some particulate is usually present no matter how the room and air are cleaned and filtered. Typically these few particulate cause no problems, but the goal is always to have the cleanest air possible during surgery. The Air Barrier System (ABS) consists of a reusable blower and a sterile nozzle. The blower feeds filtered air into the sterile disposable nozzle, which disperses a constant stream of gentle, high purity air over the surgical incision. This stream of air forms a shield over the surgical area to prevent airborne particulate from settling into the open wound. This is particularly critical for long-duration surgeries, such as procedures that involve the implantation of a prosthesis. The main objective of this research study is to determine whether the ABS can reduce the potential for surgical site infection during total hip replacement, spinal fusion, or lower extremity bypass grafting procedures. These procedures were chosen because each is a long-duration procedure which involves implantation of prosthesis.

NCT ID: NCT01553604 Completed - Clinical trials for Surgical Site Infection

Dressing Wear Time After Breast Augmentation With Prosthesis

Start date: July 2013
Phase: N/A
Study type: Interventional

This study was designed to determine whether the duration of dressing wear following augmentation mammaplasty influence skin colonization and eventually surgical site infections rates.

NCT ID: NCT01496352 Completed - Clinical trials for Surgical Site Infection

DFA-02 in Patients Undergoing Colorectal Surgery

Start date: February 2012
Phase: Phase 1/Phase 2
Study type: Interventional

This is a randomized, double-blind, placebo controlled, safety, tolerability, and pharmacokinetic dose escalation Phase II study of DFA-02 in patients undergoing colorectal surgery to evaluate the safety, tolerability and pharmacokinetics of DFA-02.

NCT ID: NCT01495117 Completed - Clinical trials for Surgical Site Infection

Study of Chlorhexidine Gluconate as a Preoperative Antisepsis

CHG
Start date: October 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine which drug (chlorhexidine gluconate vs. povidone iodine) as a preoperative antisepsis in clean-contaminated abdominal surgery (liver, hepatobiliary, small or large bowel, stomach) is effective.

NCT ID: NCT01450631 Completed - Clinical trials for Surgical Site Infection

The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions

Start date: February 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the post-surgical standard-of-care dressing to the Prevena™ Incision Management System in women undergoing Cesarean section surgery.

NCT ID: NCT01431339 Completed - Clinical trials for Surgical Site Infection

Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Start date: July 2011
Phase: Phase 3
Study type: Interventional

The primary object is to compare the early clinical efficacy (after 48-72 hours of therapy) of dalbavancin to the comparator regimen (vancomycin with the option to switch to oral linezolid) for the treatment of patients with a suspected or proved gram-positive bacterial skin or skin structure infections.