Hepatectomy With or Without the Thoraco-abdominal Approach

Surgery Clinical Trial

Official title:

Hepatectomy With or Without the Thoraco-abdominal Approach: Impact on Perioperative Outcome

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03171428
• Other study ID #: ThoraxForLiver
• Status: Completed
• Phase: N/A
• First received: May 28, 2017
• Last updated: May 31, 2017
• Start date: January 1, 2007
• Est. completion date: April 1, 2015

Study information

• Verified date: May 2017
• Source: University of Milan
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The performance of hepatectomy for liver tumors using the thoraco-abdominal approach (TAA) versus the abdominal approach (AA) is still debated.

The aim of the study is the analysis of the perioperative outcome of patients operated with or without the TAA for liver tumors.

Description:

The prospectively maintained database was queried. A 1:1 propensity score-matched analysis was applied. Among 744 patients, 246 undergoing hepatectomy with TAA and 246 undergoing hepatectomy with AA were compared. These patients were matched for baseline characteristics, underlying liver disease, comorbidity, tumor features, and extent of the resection. The rates of morbidity and mortality were the study endpoints.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 744
• Est. completion date: April 1, 2015
• Est. primary completion date: December 31, 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• First liver surgery;

• Any type of malignant liver tumor, including hepatocellular carcinoma on cirrhosis.

Exclusion Criteria:

• Previous history of liver surgery;

• Any type of benign liver tumor;

• Incomplete clinical, surgical, pathological or postoperative data;

• Patients treated with radiofrequency ablation alone or in combination with surgery were also excluded.

Related Conditions & MeSH terms

• Hepatectomy
• Liver Neoplasms
• Liver Resection
• Liver Tumors
• Surgery

Intervention

Procedure:
• Hepatectomy
Surgery for liver tumors is the removal of a part of the liver affected by a tumor.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Milan

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Short-term outcome: Occurrence of postoperative complications or death after surgery	Occurrence of postoperative complications or death after surgery	Within 90-days after the operation