Surgery Clinical Trial
This study was conducted to demonstrate the equivalence of wound outcomes between the interrupted oblique intradermal suture (OIS) and conventional interrupted intradermal suture (IS) methods
Bi-layered skin closure is one of the most common methods for closing cutaneous defects. The
deep layer is closed with a conventional interrupted intradermal suture using absorbable
materials, while the superficial layer is approximated with simple interrupted or simple
continuous suture using non-absorbable materials. The cosmetic result of bi-layered closure
is better than simple interrupted suture alone, because the interrupted intradermal suture
component plays a major role in reducing wound tension, which has the effect of minimizing
suture marks. Although the advantages of bi-layered closure are recognized, bi-layered
closure is often not used in favor of simple interrupted suture due to the fact that
interrupted intradermal suture is time consuming and more suture material is required. Thus,
if an intradermal suturing technique can be identified that takes less time and requires
less material while yielding a similar cosmetic result, patients would have more opportunity
to receive bi-layered closure and obtain a better wound outcome.
Several novel intradermal suturing techniques could be alternative to the conventional
interrupted intradermal suture technique, including buried butterfly suture, double
butterfly suture, subcutaneous inverted cross mattress suture, and interrupted oblique
intradermal suture. Among these novel techniques, interrupted oblique intradermal suture
(OIS) is recognized for its relative simplicity. OIS is easy to perform, even for beginners.
The simplicity and effectiveness of OIS increase its potential of becoming one of the
standard suturing techniques in medical practice.
OIS is very similar to conventional interrupted intradermal suture (IS), except that the
suture in OIS is canted or angled relative to the vertical plane. To perform OIS, the needle
is passed from deep to superficial dermis and canted 30°-60° from the normal vertical plane.
The needle is then inserted into the opposite wound edge from superficial to deep dermis in
a mirror-image fashion. The thread is tied with a square knot to finish the suture. The key
characteristic that distinguishes OIS from IS is that OIS involves suturing on an angle to
the vertical plane and IS involves suturing on the vertical plane.
In theory, OIS is a hybrid method that combines IS and buried horizontal butterfly suture.
OIS combines the ability of IS to reduce tension at the wound edge and the ability of
horizontal butterfly suture to provide good wound edge apposition and eversion. Because OIS
is canted, it can provide tension in both the vertical and horizontal planes. Moreover, 1
stitch of OIS should yield wound closure approximately equal to that of 2 stitches of IS due
to the same horizontal distance between 1 OIS stitch and 2 VIS stitches. Accordingly, it can
be inferred that OIS should result in a 50% reduction in both suturing time and suturing
material used.
However, OIS has the same obstacle as many other novel suturing techniques that there is
very little literature to support OIS clinically which makes usage and generalization of TIS
remain limited. It was hypothesized that OIS is equivalence to IS in wound outcome while
consumes less time and less suture material. This study aims to demonstrate the equivalence
of wound outcomes between the interrupted oblique intradermal suture (OIS) and conventional
interrupted intradermal suture (IS) methods.
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Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment
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