Ultrasound Guided Obturator Nerve Block for Total Knee Replacement (TKR)

Surgery Clinical Trial

Official title:

Comparison of Posterior Lumbar Plexus Block Plus Sciatic Nerve Block With Sciatic Plus Femoral Plus Obturator Nerve Block for Total Knee Replacement (TKR)

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01755117
• Other study ID #: TKR obturator
• Status: Recruiting
• Phase: N/A
• First received: December 18, 2012
• Last updated: April 27, 2014
• Start date: December 2012
• Est. completion date: December 2014

Study information

• Verified date: April 2014
• Source: Larissa University Hospital
• Contact: Metaxia Bareka, Medicine
• Phone: 00306947845083
• Email: barekametaxia[@]hotmail.com
• Is FDA regulated: No
• Health authority: Greece: National Organization of Medicines
• Study type: Interventional

Clinical Trial Summary

Total Knee Replacement can be performed under the combination of posterior lumbar plexus block plus sciatic nerve block. The investigators can have the same outcome by performing instead of posterior lumbar plexus block more peripheral nerve blocks. More specifically under the combination of sciatic nerve block plus femoral nerve block plus obturator nerve block.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: December 2014
• Est. primary completion date: December 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• Age 18 - 80 yrs

• ASA I - III

• TKR surgery

Exclusion Criteria:

• Coagulopathy disorders

• Infection at the puncture site for the interscalene block

• Neurologic deficit in the arm that is going to be operated

• Allergy to local anesthetics

• BMI > 35

• Psychiatric disorders

• Patient's refusal

• Problems with patient communication

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Related Conditions & MeSH terms

• Surgery
• Total Knee Replacement

Intervention

Other:
• Sciatic, femoral, obturator nerve blocks

• Sciatic nerve block, posterior lumbar plexus block

Locations

Country	Name	City	State
Greece	Larissa University Hospital	Larissa	Thessally

Sponsors (1)

Lead Sponsor	Collaborator
Larissa University Hospital

Country where clinical trial is conducted

Greece, 

References & Publications (1)

Enneking FK, Chan V, Greger J, Hadzic A, Lang SA, Horlocker TT. Lower-extremity peripheral nerve blockade: essentials of our current understanding. Reg Anesth Pain Med. 2005 Jan-Feb;30(1):4-35. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Postoperative opioid consumption		First 24 postoperative hours	No
Primary	Feasibility of TKR surgery under ultrasound guided sciatic nerve block plus femoral nerve block plus obturator nerve block measured with Pain Score on the Visual Analog Scale	If the patient complains for pain > 4 in VAS and there is no relief with fentanyl administration the anesthesia plan converts to general anesthesia with laryngeal mask	Completion of surgery	No
Secondary	Intraoperative opioid consumption for TKR surgery under ultrasound guided sciatic nerve block plus femoral nerve block plus obturator nerve block		Intaoperatively	No