Preoperative Biliary Drainage for Resectable Hilar Cholangiocarcinoma

Surgery Clinical Trial

Official title: Effect of Preoperative Biliary Drainage on Postoperative Complications in Resectable Patients With Hilar Cholangiocarcinoma(Klatskin Tumor)

Status Recruiting

Clinical Trial Summary

This study is to investigate whether preoperative biliary drainage can reduce the postoperative morbidity in patients with hilar cholangiocarcinoma.

Clinical Trial Description

Preoperative biliary drainage(PBD) or not, is a Hot Spot issue in the management of Hilar cholangiocarcinoma. Surgeons from Japan tend to perform PTBD(Percutaneous Transhepatic Biliary Drainage) before a definite operation until the total bilirubin(TB) lower than 85μmol/L. For some patients needed to perform extended curative resection, PVE(Portal Vein Embolization) is performed and thus the duration of PBD may be around six weeks and the final TB is lower than 34μmol/L. Some tend to perform a definite curative operation in a short time after diagnosis. There is no RCT research on the effect of PBD for the resectable Hilar Cholangiocarcinoma patients to date. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Cholangiocarcinoma
• Drainage
• Klatskin's Tumor
• Postoperative Complications
• Surgery

• NCT number: NCT00797121
• Study type: Interventional
• Source: Sun Yat-sen University
• Contact: Lijian Liang
• Phone: 86-20-87755766
• Email: lianglj@medmail.com.cn
• Status: Recruiting
• Phase: Phase 4
• Start date: May 2008
• Completion date: May 2013