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Surgery--Complications clinical trials

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NCT ID: NCT04638361 Completed - Clinical trials for Surgery--Complications

Laryngeal Disorders After Childhood Cardiac Surgery

RECUP-TML
Start date: August 26, 2021
Phase:
Study type: Observational

Laryngeal disorders after childhood cardiac surgery is a complication well described in the literature. However, the long term progression of the affected children has never been studied (all the studies stopped before 2 years of follow up).

NCT ID: NCT04615091 Recruiting - Clinical trials for Surgery--Complications

Non-invasive Methods and Surgical Risk Stratification in Cirrhotics Undergoing Elective Extrahepatic Surgery

Start date: August 30, 2020
Phase:
Study type: Observational

The ELASTO-SURGERY study aims to evaluate the prognostic role of portal hypertension evaluated by non-invasive methods in predicting post-operative morbidity (at 90 days) and mortality (at 365 days) in patients with advanced chronic liver disease undergoing elective extrahepatic surgery.

NCT ID: NCT04585178 Completed - Clinical trials for Surgery--Complications

Screening for Postoperative Vital Signs Abnormalities, and Particularly Hemodynamic Ones, by Continuous Monitoring Using the Biobeat Patch

Biobeat-Postop
Start date: December 15, 2020
Phase: N/A
Study type: Interventional

Brief Summary: Post-operative morbidity remains a reality as shown by the International Surgical Outcomes Study published in 2016 and 2019 and by several recent publications which focus mainly on hypotension and cardio-vascular complications. Other complications, such as respiratory depression, are less often studied. The hypothesis is that this connected patch could be used in surgical departments to detect a postoperative complication. Biobeat Technologies Ltd has developed a sensor which continuously records the photoplethysmographic waveform and allows the calculation of several physiological parameters: heart rate (HR), oxygen saturation (SpO2), systolic blood pressure (SBP), diastolic blood pressure (DBP), stroke volume (SV), cardiac output (CO), cardiac index (CI), systemic vascular resistance (SVR), respiratory rate (RR), and temperature. The objective of this study is the quantification of hemodynamic, respiratory and temperature abnormalities detected by routine monitoring (routine nursing follow-up) and continuous monitoring by the Biobeat patch during the first 72 postoperative hours.

NCT ID: NCT04579861 Recruiting - Surgery Clinical Trials

GO SOAR1: Post-Operative Morbidity and Mortality Following Gynaecological Oncology Surgery

GO SOAR1
Start date: January 19, 2021
Phase:
Study type: Observational

The Global Gynaecological Oncology Surgical Outcomes Collaborative (GO SOAR) will develop a network of gynaecological oncology surgeons, surgical departments and other interested parties that will have the long-term ability to collaborate on outcome studies. The aims of the Collaborative are to: 1. Set the research agenda through research prioritisation in gynaecological oncology surgical outcomes. 2. Gather high quality data via a centralised database accessible to all sites that perform gynaecological oncology surgery. 3. Build sustainable international research by producing protocols/guidelines. 4. Train the researchers and leaders of tomorrow by providing open access to all GO SOAR training materials. The Collaborative will lead to several studies. The first GO SOAR collaborative study (GO SOAR1) will evaluate international variation of post-operative morbidity and mortality following gynaecological oncology surgery between country groups defined by the human development index (HDI).

NCT ID: NCT04569240 Active, not recruiting - Clinical trials for Surgery--Complications

Accuracy of the Dexcom G6 Continuous Glucose Monitoring System Following Cardiac Surgery

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

This is a prospective longitudinal study to study the agreement between a novel continuous glucose monitoring system (CGMS) versus current blood glucose monitoring. Subjects in this study will have their blood glucose measured regularly every 1-3 hours with current methods in the cardiovascular intensive care unit (CVICU), and by point of care glucose using the Accuchek Inform II on the regular floors, and the CGMS at the same time will be captured. Subjects will have measurements taken throughout their stay in the CVICU and on the regular floors.

NCT ID: NCT04550156 Completed - Colorectal Cancer Clinical Trials

Evaluation of the Introduction of a Colorectal Bundle in Left Sided Colorectal Resections

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

The complication rate in colorectal surgery is high and shows a large variance depending on the patient and the treating surgeon. The primary aim of the presented study is to evaluate the introduction of a colorectal bundle to reduce the complication rate in left sided colorectal resections. The colorectal bundle is a catalog of measures consisting of several items These are for example preoperative risk stratification, antibiotic and mechanical bowel preparation and preoperative showering. The primary endpoint will be the complication rate measured as the comprehensive clinical index (CCI) within 30 days. Investigators will include patients that undergo elective or emergency left sided colorectal surgery.

NCT ID: NCT04541758 Not yet recruiting - Clinical trials for Surgery--Complications

Comparing the Efficacy of Conservative Treatment With Minimally Invasive Surgery in the Treatment of Rib Fractures

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Open, randomized, parallel controlled prospective clinical study design was used in this study.Subjects were patients with 2-4 displaced non-flail rib fractures.Operation group (Group 1) : minimally invasive internal fixation operation group under spontaneous breathing anesthesia.In the operation group of minimally invasive internal fixation under autonomic respiratory anesthesia, the fracture was determined preoperatively by chest CT+ three-dimensional reconstruction of the ribs, and the optimal incision location was determined. The fracture was exposed through as many small incisions as possible, and fixed with titanium plate or clon-type plate. During the operation, the autonomic respiratory anesthesia and paraviral nerve block technology was adopted.In the conservative group (group 2), routine treatment measures such as analgesia and chest strap fixed were adopted.The purpose of this study was to evaluate the safety, feasibility, and efficacy of minimally invasive and conservative treatment for rib fractures with different Numbers of displaced ends.

NCT ID: NCT04513262 Completed - Clinical trials for Surgery--Complications

Effects of Video-Assisted Surgery on Ventilatory Parameters

Start date: March 20, 2015
Phase:
Study type: Observational

The study investigates the effects of induced pneumoperitoneum during surgery on ventilatory parameters including peak inspiratory pressure, lung compliance, end-tidal CO2 at specific time-points: after induction of anaesthesia, after induction of surgery, one-hour and two-hours during surgery, end of surgery. The effects of pneumoperitoneum are compared between two groups of patients: patients undergoing laparoscopic surgery and patients undergoing robotic-assisted surgery. No intervention was performed in this study and the decision for type of surgery performed was made by the attending surgeon prior to study inclusion

NCT ID: NCT04501315 Completed - Critical Illness Clinical Trials

S100B in Intensive Care Patients With and Without Traumatic Brain Injury

Start date: July 1, 2007
Phase:
Study type: Observational

The neurotrophic protein S100B has been promoted as a neuromarker for decades, and to reflect the severity of brain injury. On the other hand, S100B is a tumor marker. The interpretation of its serum levels may be altered by a contribution from extracerebral sources and its renal elimination. In the present study we investigate the relevance of S100B as a prognostic factor, as well as the correlation with different CT classifications in a large cohort of patients with and without brain injury. Furthermore, we examine whether S100B is elevated in brain tumors.

NCT ID: NCT04493801 Recruiting - Clinical trials for Surgery--Complications

Incidence of Rhinological Morbidities During Endonasal Pituitary Surgery, With or Without Nasoseptal Flap

HLNS
Start date: July 23, 2019
Phase:
Study type: Observational

Determine and compare prospectively the incidence of rhinological adverse events during pituitary surgery with or without nasoseptal flap