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Surgery--Complications clinical trials

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NCT ID: NCT03963427 Active, not recruiting - Clinical trials for Breast Cancer Female

Quality of Life, Aesthetic Result and Health Economy in Breast Reconstruction

GoBreast
Start date: March 8, 2008
Phase: N/A
Study type: Interventional

A randomized clinical trial with two arms: irradiated women and non-irradiated women. Irradiated women are randomized to reconstruction with a latissimus Dorsi flap and an implant or a deep inferior epigastria perforator flap. Non-irradiated women are randomized to reconstruction with a thoracodorsal flap with an implant or with an expander and later a permanent implant in two stages.

NCT ID: NCT03959904 Recruiting - Clinical trials for Surgery--Complications

The Impact of Abdominal Wall Closure Technique on Incidence of Incisional Hernia in Kidney Transplantation

Start date: March 10, 2020
Phase: N/A
Study type: Interventional

STUDY SUMMARY Incisional hernias, or swellings of the abdominal scar after surgery, remain problematic especially after transplant surgery. This is because they can cause complications, including trapping of bowel or the transplant. This can cause life threatening emergencies but is at the very least unsightly and uncomfortable for the patient. Transplant patients are especially likely to develop hernias because of the diseases causing the renal failure and the drugs that they take to dampen the immune system. There is evidence from other surgery that the stitching methods that are used to close the wounds might decrease the risk of surgical hernias. This is achieved by placing smaller and more numerous sutures (stitches) in the wound to increase the strength of the repair. However, this has never been tested formally in transplant where it may provide significant benefit. We intend to do some initial investigation of whether using the smaller stitches may provide benefit over more traditional methods that are currently being used. We will look at early complications after surgery but also the rate of hernia formation later. We hope to improve outcomes and reduce complications for our transplant patients by doing this. In addition we will collect blood and tissue samples from both live kidney donors and the recipients to microscopically analyse their collagen to identify potential factors which may indicate risk of hernia formation.

NCT ID: NCT03949439 Completed - Clinical trials for Coronary Artery Disease

Pre-frailty and Rehospitalization in Cardiac Surgery

Start date: November 1, 2017
Phase:
Study type: Observational

Background: It has been demonstrated that pre-frailty has more adverse outcomes after cardiac surgery, however, data on prognosis and long-term evolution in pre-frailty patients after cardiac surgery without postoperative complications are still scarce. Design: To evaluate the impact of pre-frailty on functional survival in patients after cardiac surgery without complications.

NCT ID: NCT03949348 Completed - Clinical trials for Stress Urinary Incontinence

Transobturator Urethral Sling Placement With an Autologous Rectus Facia

Start date: May 1, 2016
Phase: N/A
Study type: Interventional

The investigators aimed to evaluate outcomes of transobturator urethral sling placement using autologous rectus fascia for female stress urinary incontinence at perioperatively and at 2-year follow-up.

NCT ID: NCT03942146 Completed - Smoking Cessation Clinical Trials

Smoking Cessation Prior to Gynecological Surgery

Start date: November 5, 2015
Phase: N/A
Study type: Interventional

This study evaluates whether current smokers scheduled for gynecological surgery will stop smoking to a higher extent if they or the surgeon is exposed to information on smoking cessation prior to surgery in a web-based questionnaire in the Swedish National quality register for gynecological surgery, GynOp.

NCT ID: NCT03938584 Completed - Surgery Clinical Trials

The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients

Start date: October 12, 2017
Phase: N/A
Study type: Interventional

The goal of this study is to perform a randomized clinical trial to assess the effects of vitamin C versus placebo on wound healing in mandibular fracture patients.

NCT ID: NCT03930784 Completed - Physical Activity Clinical Trials

A Real-world Study to Examine the Relationship Between Simple Physical Functioning Tests, Complications and Recovery Following Abdominal Surgery.

Start date: September 21, 2016
Phase:
Study type: Observational

Background: Complications impact physical and psychological recovery and are associated with financial cost. General physical function has not been studied in relation to the development of surgical complications in this cohort. Objective: Evaluate the physical function performance differences between those who develop complications and those who do not and determine their impact on recovery. Design: Observational Setting: The pre-operative assessment unit in the University Hospital Limerick. Patients: Forty-nine participants who were planned to undergo abdominal surgery were recruited & 43 completed the study. Main outcome measure: Demographics, physical function, lung function, surgical parameters, complications and recovery data was collected.

NCT ID: NCT03925610 Terminated - Morbid Obesity Clinical Trials

Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients

Start date: April 10, 2019
Phase:
Study type: Observational

This is an observational study of morbidly obese patients recovering from general anesthesia after weight-loss surgery. The investigators aim to assess ventilatory function and how this is influenced by the diagnosis of obstructive sleep apnea (OSA), baseline ventilatory status, as well as pharyngeal collapsibility of patients who are recovering from anesthesia and treated for pain with opioids. The investigators hypothesize that patients with OSA, chronic (baseline) hypoventilation and increased pharyngeal collapsibility, will be more vulnerable to opioid-induced ventilatory depression.

NCT ID: NCT03923699 Completed - Surgery Clinical Trials

Telemedicine Control Tower for the Operating Room: Navigating Information, Care and Safety

TECTONICS
Start date: July 1, 2019
Phase: Phase 3
Study type: Interventional

Medical errors account for thousands of potentially preventable deaths each year. With the annual increase of surgical cases there is a need for research into the potential utility of a telemedicine-based control center for the operating room to assess risk, diagnose negative patient trajectories, implement evidence-based practices, and improve outcomes.

NCT ID: NCT03923127 Completed - Clinical trials for Surgery--Complications

Transitional Care Study 3

TRICA
Start date: April 16, 2019
Phase: N/A
Study type: Interventional

In this study patients with elective surgery will wear two devices (HealthDot and Elan) after surgery in hospital and after discharge at home for up to 2 weeks (HealthDot) or 3 weeks (Elan). The HealthDot will measure heart rate, posture, activity and respiratory rate which are stored on the device as well as sent to Philips. The Elan device will measure PPG and accelerometer data which is transferred to Philips. The data collected will be used for algorithm development. Data will be analysed retrospectively and compared to readmission and adverse events to see if the events could have been predicted due to the collected data by the devices. No clinical decisions will be based on the measurements done during the study.