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Automated Postoperative Sedation After Cardiac Surgery — SEPOCA  

Anesthesia Clinical Trial

Official title:
Postoperative Sedation After Cardiac Surgery : Comparison Between Manual Administration and Automated Sedation

Clinical Trial Summary

This study compares automated administration of propofol and remifentanil guided by the Bispectral index (BIS) versus manual administration for sedation after cardiac surgery.

Clinical Trial Description

Automated sedation has the potential to improve patient care after cardiac surgery by adjusting drug doses to the minimum required for efficacy. Indeed, automated and continuous titration may avoid overdosing, improve hemodynamic stability and also decrease the mean time to tracheal extubation. Medsteer SAS developed a controller, EasyTiva device, allowing the closed-loop coadministration of propofol and remifentanil, guided by a Bispectral Index (BIS) monitor. Automated sedation is so facilitated by the BIS which permits continuous monitoring of electrocortical activity. This randomized monocentric trial compares the automated administration with manual intravenous administration of propofol-remifentanil for maintaining adequate depth of hypnosis (BIS 55-75) during sedation after cardiac surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03517735
Study type Interventional
Source CMC Ambroise Paré
Contact
Status Terminated
Phase N/A
Start date December 17, 2018
Completion date March 30, 2019
View Details
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