Superficial Basal Cell Carcinoma Clinical Trial
Official title:
Cure Rates of Superficial Basal Cell Carcinoma Following 1 Versus 3 Cycles of Electrodessication & Curettage: A Randomized Prospective Study
This is a prospective, randomized clinical trial conducted at the Unviersity of Wisconsin (UW) Dermatology Clinic located at 1 S. Park Street, Madison, WI 53715. There are no controls. Subjects meeting eligibility criteria are randomly divided into one of two treatment groups (ED&C x 1 cycle or ED&C x 3 cycles) using computer generated random numbers. One cycle of ED&C is defined according to standard technique currently employed. It involves scraping away the tumor with a curette (ring- shaped instrument) and then burning the curetted site with a small electric needle (electrodessication). During Visit 1, the surgical site is marked, local numbing medication is injected, and 1 or 3 cycles of ED&C is/are performed by board-certified dermatologists or a dermatology resident under the direct supervision of a board certified dermatologist. All follow-up visits (3, 6, 9, and 12 months after Visit 1) include skin evaluations by the physician who performed the ED&C. The lesion site is examined, measured, and photographed for clinical evidence of recurrence, as defined by a new lesion within the previously treated site. If there is evidence of possible tumor recurrence at the treated surgical site during Visit 2, 3, 4 or 5, then the lesion will be biopsied using a shave procedure.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT04552990 -
Use of Jet-injection in Photodynamic Therapy for Basal Cell Carcinoma
|
Phase 2 | |
| Active, not recruiting |
NCT03573401 -
Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Superficial Basal Cell Carcinoma (sBCC) With Photodynamic Therapy (PDT).
|
Phase 3 | |
| Completed |
NCT03012009 -
Laser Assisted Drug Delivery in the Treatment of Superficial Non Melanoma Skin Cancer: a Randomized Controlled Trial
|
N/A | |
| Completed |
NCT02270645 -
Randomized Pilot Study of Treatment for BCC Using the Multiplex 595/1064 nm Laser
|
N/A | |
| Completed |
NCT00469417 -
Metvix PDT Versus Cryotherapy in Patients With Primary Superficial Basal Cell Carcinoma
|
Phase 3 | |
| Recruiting |
NCT05381597 -
5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer
|
Phase 2/Phase 3 | |
| Completed |
NCT00604890 -
Dose-Ranging Clinical Trial of Topical Creams Containing API 31510 for the Treatment of Superficial Basal Cell Carcinoma
|
Phase 1/Phase 2 | |
| Completed |
NCT00189306 -
Open-label Study to Evaluate Clearance of Superficial Basal Cell Carcinoma After Use of Imiquimod 5% Cream
|
Phase 3 | |
| Recruiting |
NCT05157763 -
A Study to Evaluate the Safety and Efficacy of EscharEx (EX-02) in the Treatment of Basal Cell Carcinoma
|
Phase 1/Phase 2 | |
| Recruiting |
NCT04744935 -
Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma
|
N/A | |
| Completed |
NCT05628714 -
A Patient Decision Aid for Patients With Superficial Basal Cell Carcinoma
|
||
| Completed |
NCT00432185 -
To Determine the Maximum Tolerated Dose Level (MTD) of PEP005 Topical Gel in Patients With sBCC
|
Phase 2 | |
| Recruiting |
NCT01491711 -
Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate
|
Phase 4 | |
| Completed |
NCT04470726 -
Safety and Efficacy of AIV001 on Low Risk Basal Cell Carcinoma
|
Phase 1/Phase 2 | |
| Completed |
NCT01325688 -
PEP005 Gel - Evaluation of the Safety and Efficacy of Ingenol Mebutate Gel on a Superficial Basal Cell Carcinoma on the Trunk or Extremities
|
Phase 2 | |
| Recruiting |
NCT05713760 -
Proof of Concept Study to Access Superficial Basal Cell Carcinoma in Adults
|
Phase 2 |