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Suicide clinical trials

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NCT ID: NCT05867316 Recruiting - Emotion Regulation Clinical Trials

Supplementing Brief Psychotherapy With a Mobile App

Start date: September 14, 2023
Phase: N/A
Study type: Interventional

Suicide is among the leading causes of death worldwide, and the risk of suicide is highest in the period immediately following discharge from inpatient psychiatric care.1Importantly, despite the enormously elevated risk during this period, nearly 50% of patients do not attend scheduled therapy after discharge. Even among those who do attend therapy, however, the skills learned in treatment may be difficult to use during the highly distressing time leading up to and during a suicide crisis. Most traditional treatments are not designed to be effective during a suicide crisis. In order to reduce the risk of suicidal thoughts and behaviors in general and specifically during the post-discharge period, interventions are needed that: (1) are easily adhered to and (2) are accessible and effective during a suicide crisis. As such, the purpose of this research study is to test an innovative, new intervention in order to develop an effective and accessible intervention for those at high risk for suicide

NCT ID: NCT05848089 Recruiting - Suicidal Ideation Clinical Trials

Real-time Intervention for Suicide Risk Reduction

Start date: September 25, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to determine whether learning three skills for managing negative emotions and receiving reminders via smartphone to practice these skills reduces how often and how intensely one experiences emotional distress and suicidal thoughts.

NCT ID: NCT05847582 Not yet recruiting - Suicide Clinical Trials

mHealth-supported Skills Training for Alcohol-Related Suicidality Phase 3

mSTARS
Start date: July 1, 2025
Phase: N/A
Study type: Interventional

Suicide is a high priority public health problem and an increasingly prevalent alcohol-related consequence. One-third of people who die by suicide consume alcohol at hazardous rates in the year preceding death. Most people in an acute suicide crisis who present for treatment are admitted to acute psychiatric hospitalization. Yet, the 30-day period following discharge from hospitalization is by far the riskiest period for another suicide crisis. The specific aim for this project is to evaluate the feasibility and acceptability of an intervention called mHealth-supported Skills Training for Alcohol-Related Suicidality (mSTARS). Thirty-five inpatients with suicidal thoughts or behaviors who misuse alcohol will be randomized to one of three study conditions -- mSTARS, treatment as usual, or treatment as usual with skills training.

NCT ID: NCT05847504 Not yet recruiting - Suicide Clinical Trials

mHealth-supported Skills Training for Alcohol-Related Suicidality

mSTARS
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Suicide is a high priority public health problem and an increasingly prevalent alcohol-related consequence. One-third of people who die by suicide consume alcohol at hazardous rates in the year preceding death. Most people in an acute suicide crisis who present for treatment are admitted to acute psychiatric hospitalization. Yet, the 30-day period following discharge from hospitalization is by far the riskiest period for another suicide crisis. The specific aim for this project is to use a successive cohort design to iteratively develop an intervention called mHealth-supported Skills Training for Alcohol-Related Suicidality (mSTARS). The study team will adapt and iteratively refine a cognitive-behavioral skills training intervention in emotion regulation to be administered in an acute care setting and paired with a post-discharge mHealth app that encourages application of these skills to real life. Two cohorts of five participants each will be enrolled in the project. Participants will complete mSTARS, an intervention that combines inpatient skills training and the mHealth telephone app. Upon completion of the 30-day period, participants will complete self-report measures and participate in an interview designed to evaluate their experience with the mSTARS intervention.

NCT ID: NCT05842863 Recruiting - Clinical trials for Suicide and Self-harm

Combined Dialectical Behavior Therapy and Digital Cognitive Behavioral Therapy for Insomnia for Adolescents at High Risk for Suicide

Start date: June 15, 2024
Phase: N/A
Study type: Interventional

The proposed research addresses the urgent need to reduce suicide rates among teens. This will be the first study that the investigators know of that will examine the feasibility and preliminary effectiveness of augmenting a suicide-focused treatment (Dialectical Behavior Therapy, [DBT]) with an evidence-based treatment protocol for insomnia (a digital version of Cognitive Behavioral Therapy for Insomnia [CBT-I]). The goal of this clinical trial is to learn providing insomnia treatment in conjunction with suicide-focused treatment leads to greater reductions in suicidality and self-harm than suicide-focused treatment alone. Participants will be randomly assigned to receive 6 months of DBT plus CBT-I or to DBT alone and will complete research assessments measuring suicidal ideation, self-harm behavior and insomnia symptoms every four weeks over the course of the study, as well as one post-treatment follow-up assessment. Participants will also wear a device on their wrist (like a Fitbit or wristwatch) for 10 days following each assessment to collect data about their sleep.

NCT ID: NCT05837026 Not yet recruiting - Suicide Clinical Trials

A Health System/Community Partnership for Enhanced Outreach to Prevent Suicide Attempts

Start date: July 2026
Phase: N/A
Study type: Interventional

The goal of this study is to test an enhanced outreach intervention (EOI) delivered by Samaritans of Boston (a community organization that provides support during mental health crises) for people after they leave an emergency department (ED) visit for suicidal thoughts. The main questions it aims to answer are: - Does the EOI reduce suicide-related behaviors? - Does the EOI increase outpatient treatment attendance? - Is the EOI acceptable and feasible? - Can the EOI be delivered with fidelity by Samaritans? Participants will be randomized to the EOI plus care as usual or care as usual alone. Participants in the EOI plus care as usual group will: - Receive outreach (by call or text) at a planned time once per week for the next 12 weeks. During these conversations, Samaritans staff will ask participants questions about their suicidal thoughts and behaviors, develop and review a list of coping skills to use if they have suicidal thoughts, and discuss plans for receiving mental health care. - Receive caring messages from Samaritans staff at least once per week. - Receive standard care that hospitals give for patients who present with suicidal thoughts. - Be asked to complete monthly self-report questionnaires. For care as usual alone, participants will: - Receive standard care that hospitals give for patients who present with suicidal thoughts. - Be asked to complete monthly self-report questionnaires.

NCT ID: NCT05834660 Recruiting - Suicidal Ideation Clinical Trials

SAFETY-A for Promoting Equity in Suicide Prevention Outcomes in Schools

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

This study will adapt Safe Alternatives For Teens and Youth - Acute (SAFETY-A) for implementation in low-resourced school districts to reduce racial/ethnic disparities in mental health service use (MHS) following identification of suicide risk in youth. SAFETY-A will be adapted to fit the organizational context of school districts and to reduce mistrust of MHS, internalized stigma, and concealment of youth emotional distress that arise in school suicide risk assessments with Asian American and Latinx students. Following a prototyping case series, a feasibility trial will assign four districts to the timing of SAFETY-A implementation to generate preliminary data on feasibility and impacts on proposed mechanisms and youth MHS utilization and clinical outcomes across racial/ethnic groups.

NCT ID: NCT05825820 Not yet recruiting - Suicide Clinical Trials

Pilot Study of Health System/Community Partnership for Enhanced Outreach to Prevent Suicide Attempts

Start date: January 2026
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test an enhanced outreach intervention (EOI) delivered by Samaritans of Boston (a community organization that provides support during mental health crises) for people after they leave an emergency department (ED) visit for suicidal thoughts. The main questions the trial aims to answer are: - Is the EOI feasible and acceptable? - Can the EOI be delivered with fidelity by Samaritans staff? Participants will: - Receive outreach (by call or text) once per week for 12 weeks after ED visit. During these conversations, Samaritans staff will ask participants questions about their suicidal thoughts and behaviors, develop and review a list of coping skills to use if they have suicidal thoughts, and discuss plans for receiving mental health care. - Receive caring messages from Samaritans staff at least once per week. - Be asked to complete monthly self-report questionnaires, and participate in a phone interview with study staff at the end of the study.

NCT ID: NCT05816421 Enrolling by invitation - Clinical trials for Post Traumatic Stress Disorder

Adaptation and Evaluation of the KEEP Model

Start date: May 16, 2022
Phase: N/A
Study type: Interventional

This study capitalizes on an opportunity to formally evaluate local adaptations of "Keeping Foster and Kinship Parents Supported and Trained" (KEEP), an evidence-based foster parent intervention, to reduce mental health disparities among child welfare-involved youth and improve care quality and long-term outcomes for Native, Hispanic/Latino, Black/African American, and sexual and gender minority youth. The knowledge gained from the study will impact all current and future large-scale implementations of KEEP and will bolster our scientific understanding the impact of KEEP on youth mental health outcomes.

NCT ID: NCT05796531 Recruiting - Suicidal Ideation Clinical Trials

Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization

TEC
Start date: March 31, 2023
Phase: N/A
Study type: Interventional

Suicide is the 2nd leading cause of death among adolescents, with the highest risk period for suicide being the month following psychiatric inpatient hospitalization. The investigators propose testing a brief, scalable intervention using evaluative conditioning aimed at reducing suicidal thoughts and behaviors among adolescents during and after inpatient hospitalization. Scalable interventions, such as the one proposed that reduce suicide risk during this markedly high-risk period, could result in large-scale decreases in suicide death.