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Suicidality clinical trials

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NCT ID: NCT06229132 Completed - Depression Clinical Trials

Mental Health Support for Transgender and Gender-expansive Individuals

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

This study will evaluate an intervention's feasibility, acceptability and efficacy potential in a one-arm trial with Romanian transgender and gender diverse (e.g., gender non-binary) (TGD) individuals who report depression or anxiety. The intervention will consist of 16 1-hour sessions delivered by our trained therapists on Zoom. These sessions are based on 6 principles of LGBTQ-affirming CBT, as follows: (1) normalizing mood and anxiety as a common response to LGBTQ related stress; (2) challenging persistent, inflexible LGBQ-related stress-induced cognitions; (3) encouraging assertive behavior and open self-expression to effectively cope with the consequences of LGBTQ-related stress; (4) validating lesbian, gay, bisexual, and transgender (LGBTQ) clients' unique strengths; (5) building authentic relationships as an essential resource for LGBTQ people's mental health; and (6) recognizing intersectional identities as a source of stress and resilience.

NCT ID: NCT06073964 Completed - Clinical trials for Post-Traumatic Stress Disorder

GBV, Primary Trauma & Trauma Resilience & Understanding Self-help Therapy Utilization in Uganda

GBV
Start date: November 23, 2022
Phase: N/A
Study type: Interventional

The goal of this community-based interventional study was to determine the effectiveness of the 'Trauma Resilience & Understanding Self-help Therapy' (TRUST) in managing domestic violence & primary trauma among formerly Internally Displaced Persons (fIDPs) in northern Uganda. The main questions it aimed to answer were: - What was the level of utilization and short-term effects of the TRUST intervention on the experiences of domestic violence and high levels of primary trauma among fIDPs living in northern Uganda who would have been using TRUST within their communities after completing the training in the community-based TRUST utilization? - What were the clinical indications of the TRUST intervention and psychological operators among fIDPs living in northern Uganda who would have been using TRUST within their communities to manage their experiences of domestic violence and high levels of primary trauma? Participants found to have experienced domestic violence in the last one year and were having high levels of primary trauma were randomly assigned to the intervention group that was trained in the utilization of the TRUST within their communities and then followed up for 12 weeks (TRUST group). The investigators then compared the results obtained from the TRUST group with those attained from an age and gender cross-matched control group of fIDPs who were not trained in the utilization of the TRUST within their communities (Control group). This was done to see if the community-based utilization of the TRUST intervention changed the levels of primary trauma & experiences of domestic violence among its users (TRUST group) when compared to the non-users (Control group).

NCT ID: NCT05541406 Recruiting - Depression Clinical Trials

Efficacy of a Multi-level School Intervention for LGBTQ Youth

Start date: September 14, 2022
Phase: N/A
Study type: Interventional

Efficacy of a Multi-level School Intervention for LGBTQ Youth

NCT ID: NCT05177146 Recruiting - Suicidality Clinical Trials

Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression

DEEPP
Start date: May 4, 2022
Phase: N/A
Study type: Interventional

Bipolar disorder is characterized by manic episodes and episodes of extreme depressive feelings, also known as bipolar depression (BD). Although clinical data does not suggest significant differences in the severity of depressive symptoms between bipolar and unipolar depression, patients with BD are found to be more likely to experience suicidal ideation and suicide attempts. Innovative treatments for suicidality in patients with BD are needed to address tolerability and slow effect limitations of current interventions. Using an open label pilot study, this trial aims to examine the effect of Intravenous (IV) ketamine treatment on acute suicidality in patients with BD. Moreover, the study aims to explore the neurophysiological mechanisms of ketamine's action directly from the cortex in patients with BD, in order to understand the biological mechanism underlying ketamine's therapeutic action.

NCT ID: NCT04197765 Active, not recruiting - Suicidality Clinical Trials

acTBS Treatment for Inpatient Subjects With Suicidality

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

This is a pilot study to analyze the benefit of accelerated continuous Transcranial magnetic stimulation for inpatient subjects suffering with suicidal ideation. This study will enroll 40 inpatient subjects recruited from the Resnick Neuropsychiatric hospital. Subjects will be blinded and randomized to active or sham TMS treatment and will receive up to 5 assigned treatments per day. Subjects will also be asked to complete mood surveys throughout their participation. Participation in this study will last 7-10 days depending on scheduling.

NCT ID: NCT03751020 Completed - Depression Clinical Trials

Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults

Project LEAP
Start date: October 27, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression, suicidality, substance abuse and HIV risk behaviors.

NCT ID: NCT03732300 Completed - Suicide, Attempted Clinical Trials

Attempted Suicide Short Intervention Program: a Randomized Controlled Trial

EASI
Start date: December 1, 2018
Phase: N/A
Study type: Interventional

"Attempted Suicide Short Intervention Program" (ASSIP) is a brief psychotherapy intervention after suicide attempts in psychiatric patients. The study aims to analyse the efficacy in a controlled trial by comparing number of patients with suicide attempts in a control group with treatment as usual and an intervention group with treatment as usual and ASSIP intervention. Further, the study aims at indentifying electrophysiological, sociodempgraphical or smartphone-derived parameters for prediction of further suicide attempts.

NCT ID: NCT03114917 Completed - Psychosis Clinical Trials

Cognitive AppRoaches to coMbatting Suicidality

CARMS
Start date: May 12, 2017
Phase: N/A
Study type: Interventional

This is a randomised controlled trial which investigates the effectiveness of CARMS (Cognitive AppRoaches to coMbatting Suicidality) therapy in reducing suicidal thoughts and how well CARMS works in practice within the NHS. The trial will compare two groups of people with psychosis who are using NHS mental health services. One group will carry on with their usual treatment. The other group will be offered 24 weekly sessions of CARMS therapy, plus their usual treatment.

NCT ID: NCT03085108 Completed - Suicidality Clinical Trials

A Study to Assess the Validation and Mapping of the Suicide Ideation and Behavior Assessment

Start date: March 31, 2017
Phase:
Study type: Observational

The main purpose of this cross-sectional study is to generate data to support the psychometric properties of the Suicide Ideation and Behavior Assessment Tool (SIBAT) and validate its use in participants at imminent risk of suicide.

NCT ID: NCT01334372 Completed - Suicidality Clinical Trials

Intensive Outpatient Treatment for Suicidal Veterans

CAMS
Start date: February 2007
Phase: N/A
Study type: Interventional

This investigation is a feasibility study conducted in a VA outpatient treatment setting. The study is designed to test the feasibility of implementing a novel way of working with suicidal patients, the Collaborative Assessment and Management of Suicidality (CAMS). The primary purpose of the proposed project is to determine if it is possible to train clinicians working in the Mental Health Clinic at the Denver VA Medical Center (VAMC) to utilize this therapeutic framework. This project is extremely timely in relation to expectations of future increased clinical demands among potentially high-risk Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) veterans who may become suicidal in the years to come.