Suicidal Depression Clinical Trial
Official title:
Cognitive, Sleep, Neurophysiological Markers Among Suicidal Depressed Patients
Verified date | February 2024 |
Source | Assiut University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
evaluation whether suicidal major depressive disorder patients show a specific pattern of cognitive, sleep and neurophysiologic impairment as compared to non- suicidal major depressive disorder patient, and studying the correlation between the cognitive impairment, the sleep disturbance and the neurophysiologic impairment and suicidal behaviour Studying the cognitive profile in suicidal patient including studying, Comprehension, Attention, language production, reasoning, problem solving and decision making
Status | Completed |
Enrollment | 120 |
Est. completion date | January 1, 2023 |
Est. primary completion date | December 1, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria:I) patients a. Inclusion criteria: 1. Suicidal attempters, suicidal ideators, non-suicidal depressed were all diagnosed with major depression, or Bipolar disorder (BD) (depressive phase) by statistical manual of mental disorders. Patients meeting DSM-5 criteria. (APA-2013) 2. all participant provided written informed consent 3. age group above 18 years old II) control a. Inclusion criteria: 1. Match with the subjects in age group "above 18 years old" 2.no history of suicide attempt or ideation 3. no history of psychiatric disorder Exclusion Criteria: 1. other psychiatric disorders 2. electroconvulsive therapy in the Previous six months 3. Neurologic disorders including stroke, epilepsy, brain injury and sensory disorders that precluded participating in cognitive assessment. |
Country | Name | City | State |
---|---|---|---|
Egypt | Assiut University | Assiut |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Egypt,
Hassan, Wageeh .A.N., Noamany, M.M.(2020). . A clinical study of suicide in patients admitted in psychiatry unit in Assiut University. Middle East Current Psychiatry 27, 26
W. S. F. Pickering; Geoffrey Walford (2000). Durkheim's Suicide: a century of research and debate. Psychology Press. p. 25.
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Cognition among Suicidal Depressed patients | to determine the cognitive impairment among depressed suicidal patient compared to not depressed persons and to depressed non suicidal patients by 1-Mini-mental state examination: It as a basic tool used to assess the cognitive function; it includes tests of orientation, attention, memory, language and visual-spatial skills
Montreal cognitive assessment scale: The test is a one-page 30-point test administered in approximately 10 minutes. Each participant had the test individually. it was used to assess several domains of cognition such as the short term memory recall task (5 points) involves two learning trials of five nouns and delayed recall after approximately 5minutes |
one day | |
Primary | sleep among Suicidal Depressed patients | Epworth sleepiness scale:
The Epworth Sleepiness Scale (ESS) is a scale intended to measure daytime sleepiness that is measured by use of a very short questionnaire. This can be helpful in screening of sleep disorders. |
10 minutes | |
Primary | neurophysiological marker among Suicidal Depressed patients | Standard Electroencephalogram "EEG":
Conventional EEG will be done using the 8 channels Nihon Kohden machine '4217' employing scalp electrodes placed according to the international 10-20 system with bipolar and referential montages . for evaluation of power in alpha band |
1 hour |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03014362 -
TMS for Suicidal Crisis in Active Duty SMs
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N/A |