Home Treatment for Individuals Suffering From Severe Addictive Disorders

Substance Use Disorders Clinical Trial

Official title:

A Pilot Study on Home Treatment for Individuals Suffering From Severe Addictive Disorders

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05563363
• Other study ID #: not yet available
• Status: Recruiting
• Phase: N/A
• Start date: December 1, 2022
• Est. completion date: June 30, 2025

Study information

• Verified date: March 2024
• Source: University Hospital, Geneva
• Contact: Louise Penzenstadler, MD
• Phone: +41223725750
• Email: Louise.E.Penzenstadler[@]hcuge.ch
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Home Treatment (HT) has been successfully implemented in adult psychiatry in several countries including Switzerland. Patients with addiction problems were generally excluded even if the latter was not the main diagnosis. On the other hand, community treatments have successfully been established for these individuals. The investigators have recently offered HT to persons with severe addictive disorders which was well accepted.

The investigators intend to conduct a pilot study to prepare a large-scale study if successful. The investigators intend to compare HT to treatment as usual (regular inpatient treatment) on a specialized ward with respect to readmission rates during 6 months after discharge. The data show that 70.8% of all readmissions occur during the first 6 months. Therefore, a period of 6 months is considered an adequate time interval to sufficiently answer this pilot study's question.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 40
• Est. completion date: June 30, 2025
• Est. primary completion date: December 31, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Substance use disorder

• age 18 or above

• sufficient french language skills

• competent subjects

• consent to randomization progress

Exclusion Criteria:

• organic brain disease or developmental disorder

• non voluntary admission

• severe somatic comorbidity

• History of complicated substance withdrawal

• acute suicidal ideation

• aggressive behavior

• acute psychiatric disease such as mania or psychosis

• distance to center (must be reachable within 60 minutes)

Related Conditions & MeSH terms

• Substance Use Disorders
• Substance-Related Disorders

Intervention

Other:
• Hospital-like treatment in patients' home
Hospital-like treatment in patients' home. Caregivers, medical doctors and social workers will make several visits per day to the patients' home. 24/7 contact is available.
• standard inpatient treatment
Inpatient treatment on addiction ward

Locations

Country	Name	City	State
Switzerland	Geneva University Hospital	Geneva

Sponsors (1)

Lead Sponsor	Collaborator
Louise Penzenstadler

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	readmission rates	Number of readmissions to hospital during the 6 months following discharge	6 month post-discharge
Secondary	time to readmission	Number of days between discharge and readmission during the 6 months following discharge	6 months
Secondary	length of hospitalization	total number of days spent in hospital during the 6 months following discharge	6 months
Secondary	number of emergency room visits	number of emergency room visits during the 6 months following discharge	6 months
Secondary	clinical outcome	clinical outcomes measured with Health of the Nation Outcome scale (HoNOS) scoring 0 (no symptoms) to 48 (high symptom level) and the Brief Symptom Check-List (short form of the Brief Symptom Inventory), scoring 0-53 items (higher score = more symptoms). Measured at the start and end of intervention/hospital treatment.	6 months
Secondary	patient satisfaction	Patient satisfaction measured with the S-ANQ (https://www.anq.ch/en/), a questionnaire used by all Swiss hospitals to measure patient satisfaction with treatment. The questionnaire includes 6 questions which are marked from 0 not at all satisfied to 5 = very satisfied. Scoring 0 (not at all satisfied) to 30 (very satisfied)	6 months