Substance-Related Disorders Clinical Trial
Official title:
Cognitive Rehabilitation for Opioid Abuse-related Cognitive Impairment
Research has consistently found that cognitive impairment is common in persons with a history
of substance abuse. The most commonly identified impairments across all substances are in
attentional and working memory functioning and executive functioning; opioid-specific
research finds that memory is an additional area of common impairment. Initial research in
applying cognitive rehabilitation methods to substance abuse have shown it to be helpful
overall.
To develop a cognitive rehabilitation intervention that is effective for opioid abuse, this
study will adapt a cognitive training program that has been shown to be effective in other
patient groups. Patients in a residential opioid-abuse treatment program will undergo a
cognitive evaluation and then be assigned to receive the 4-week cognitive intervention or the
4-week placebo control arm. It is expected that the intervention group will show greater
gains on the cognitive post test and will have higher rated treatment adherence and opioid
treatment program completion rates.
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