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An Open-Label Trial of Repetitive Transcranial Magnetic Stimulation for Opioid Use Disorder

Substance-Related Disorders Clinical Trial

Official title:
An Open-Label Trial of Repetitive Transcranial Magnetic Stimulation for Opioid Use Disorder

Clinical Trial Summary

The purpose of this study is to understand the role of repetitive Transcranial Magnetic Stimulation (rTMS) in reducing opioid and other substance use and craving and improving thinking skills.

Clinical Trial Description

The overarching goal of this study is to investigate a form of neuromodulation, rTMS, as an adjunctive treatment for OUD by evaluating the impact of rTMS on substance use, craving and inhibitory control, factors which contribute to relapse. The primary outcome will be the assessment of whether rTMS reduces substance use. Additional exploratory outcomes include the assessment of whether rTMS applied to the DLPFC provides neuromodulatory effects through the assessment of craving, inhibitory control, and functional connectivity via MRI. The targeted sample size for this open-label study, where all enrolled subjects will receive 9 sessions of active rTMS over 3 weeks. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04157062
Study type Interventional
Source West Virginia University
Contact James J. Mahoney, Ph.D.
Phone (304) 293-1822
Email james.mahoney@hsc.wvu.edu
Status Recruiting
Phase N/A
Start date September 30, 2021
Completion date October 1, 2025
View Details
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