Medical Office Intervention for Adolescent Drug Use - Attention Study Supplement

Substance-related Disorders Clinical Trial

Official title:

Medical Office Intervention for Adolescent Drug Use - Research Supplement for Under-represented Minorities

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00593034
• Other study ID #: R01DA014553-03S1
• Status: Completed
• Phase: N/A
• First received: January 3, 2008
• Last updated: March 7, 2011
• Start date: February 2007
• Est. completion date: February 2008

Study information

• Verified date: March 2011
• Source: Children's Hospital Boston
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

This study will use the CCPT II to assess attention in 12-21 year olds enrolled in a randomized controlled trial of a brief behavioral treatment for substance abuse.

This study will describe at baseline levels of attention using a well validated instrument (Connors Continuous Performance Test II) and explore the association between attention levels and substance use. The primary study hypothesis is that lower initial levels of substance use (as measured by percent days abstinent) will be associated with higher attention levels. We envision that this data will inform a better understanding of how attention may modify treatment response.

Description:

Research among adolescents with substance use problems presents unique challenges to investigators. Issues with recruitment, confidentiality, and follow-up have been cited as common limitations to research in this area. One likely contributor to decreased treatment persistence and follow-up is the limited ability to sustain attention that many adolescents, especially those with substance problems, may manifest. (Taper, 2002) Thus, assessing attention before beginning substance abuse treatment has the potential not only to inform the science of adolescent addiction medicine, but also to guide the development of therapies to specifically address attention deficits among adolescent substance users. Adolescent outpatients being treated for substance problems have not been systematically studied for clinical or subclinical attention levels.

The primary aims this study are as follows:

1. To test the feasibility of administering the Connors Continuous Performance Test II (CCPT II), a well validated measure of attention, to a sample of 12-21 year old patients receiving treatment for substance abuse.

2. To obtain baseline descriptive statistics on the CCPT II in a previously understudied group of young patients receiving treatment for substance abuse.

3. To estimate the magnitude of the association between substance use and levels of attention at baseline before treatment.

4. To explore the degree to which attention may affect response to substance abuse treatment in general and specifically motivational interviewing.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 42
• Est. completion date: February 2008
• Est. primary completion date: February 2008
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 12 Years to 21 Years

Eligibility

Inclusion Criteria:

• CRAFFT score of 1 or more

• Have used cannabis, alcohol or another drug on at least two occasions during the 30 days preceding their visit

• Can read and understand English

Exclusion Criteria:

• Require immediate hospitalization or referral to residential substance abuse treatment

• Will not be available to complete the study assessments over the next 9 months.

Study Design

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Substance-related Disorders

Locations

Country	Name	City	State
United States	Children's Hospital Boston	Boston	Massachusetts

Sponsors (1)

Lead Sponsor	Collaborator
Children's Hospital Boston

Country where clinical trial is conducted

United States, 

References & Publications (2)

Knight JR, Sherritt L, Shrier LA, Harris SK, Chang G. Validity of the CRAFFT substance abuse screening test among adolescent clinic patients. Arch Pediatr Adolesc Med. 2002 Jun;156(6):607-14. — View Citation

Knight JR, Shrier LA, Bravender TD, Farrell M, Vander Bilt J, Shaffer HJ. A new brief screen for adolescent substance abuse. Arch Pediatr Adolesc Med. 1999 Jun;153(6):591-6. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Score on the Connors Continuous Performance Test II (CCPT II)		Baseline	No
Secondary	Percentage of days abstinent		6 months	No

External Links

•   Web site for the Center for Adolescent Substance Abuse Research, parent research group for the project.