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New Approaches to Cocaine Abuse Medications (A) - 6

Substance-Related Disorders Clinical Trial

Official title:
New Approaches to Cocaine Abuse Medications (A)

Clinical Trial Summary

The purpose of this study is to measure the effect of desipramine in cocaine abusers selected for major depression or dysthymia.

Clinical Trial Description

This is a randomized, 12-week, double-blind, 'placebo-controlled trial of outpatients meeting DSM-III-R criteria for cocaine dependence and major depression or dysthymia (by SCID interview). Participants were treated with desipramine, up to 300 mg per day, or matching placebo. All patients received weekly individual manual-guided relapse prevention therapy. Weekly outcome measures included the Clinical Global Impression Scale, self-reported cocaine use and craving, urine toxicology, and the Hamilton Depression Scale. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00000271
Study type Interventional
Source New York State Psychiatric Institute
Contact
Status Completed
Phase Phase 2
Start date January 1995
Completion date October 2002
View Details
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