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NCT00000250 Clinical Trial

Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2

Substance-Related Disorders Clinical Trial

Official title:
Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00000250
Other study ID # NIDA-08391-2
Secondary ID R01DA008391R01-0
Status Completed
Phase Phase 2
First received September 20, 1999
Last updated May 26, 2015
Start date December 1993
Est. completion date May 1995

Study information
Verified date May 2015
Source University of Chicago
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Interventional

Clinical Trial Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To evaluate: cold water immersion modulates the reinforcing effects of nitrous oxide in healthy volunteers.

Recruitment information / eligibility
Status Completed
Enrollment 12
Est. completion date May 1995
Est. primary completion date May 1995
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 21 Years to 32 Years
Eligibility Please contact site for information.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• 0% N2O
Subjects will inhale 100% oxygen with no N2O for 25 min then immerse forearm in warm water and cold water
• 40% N2O
Subjects will inhale 40% N2O then immerse forearm in warm water and cold water

Locations
Country Name City State
United States University of Chicago, Anesthesia & Critical Care Chicago Illinois

Sponsors (2)
Lead Sponsor Collaborator
University of Chicago National Institute on Drug Abuse (NIDA)

Country where clinical trial is conducted

United States, 

References & Publications (1)

Experimentall Clinical Psycopharmacoly 1995, 3(2):148-155

Outcome
Type Measure Description Time frame Safety issue
Primary Subject's choice of intervention After sampling trials No
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