Improving Substance Abuse Treatment Aftercare Adherence and Outcome

Substance Dependence Clinical Trial

Official title:

Improving Substance Abuse Treatment Aftercare Adherence and Outcome

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00057187
• Other study ID #: IIR 99-282
• Status: Completed
• Phase: N/A
• First received: March 27, 2003
• Last updated: April 6, 2015
• Est. completion date: January 2005

Study information

• Verified date: February 2007
• Source: VA Office of Research and Development
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

Although substance abuse treatment continuing care participation is strongly related to positive treatment outcomes, participation rates are low and few interventions have been developed that improve continuing care adherence and outcome.

Description:

Background:

Although substance abuse treatment continuing care participation is strongly related to positive treatment outcomes, participation rates are low and few interventions have been developed that improve continuing care adherence and outcome.

Objectives:

The objectives of the study were: 1) to compare the effectiveness of an aftercare intervention consisting of a participation contract, attendance prompts, and attendance reinforcers (CPR) to a standard treatment (STX) on adherence to therapy; and 2) to assess the effects of this intervention on treatment outcome

Methods:

We recruited 150 veterans from the Salem VAMC�s SARRTP who could participate in aftercare. Our population is similar to those in other VA�s (97% male, 54% Caucasian, 46% minority, 49 years mean age, 44% alcohol dependent only, 56% drug dependent, and 44% with a dual diagnosis). In this randomized clinical trial, treatment adherence and outcome were measured at baseline and 3-, 6- and 12-months after participants entered treatment using interviews, questionnaires, alcohol and drug screens, VA medical records, and therapist ratings. The study design is a repeated measures nested cohort design, with an intervention and a standard care group. The primary outcome, abstinence rate, will be analyzed using a logistic regression model in which the parameters of interest are estimated using Generalized Estimating Equations (GEE).

Status:

Participant recruitment and follow-up interviews were completed in June 2003 and August 2004, respectively. The HSR&D final report was submitted in April 2005. The main results paper and additional papers will be submitted for publication in 2005.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 157
• Est. completion date: January 2005
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

All graduates of the Salem VA's SARRTP who: live within a 60 minute drive of the Salem VAMC, or 1 of our 5 SARRTP outreach clinics; have transportation and a job schedule that allows them to attend outpatient aftercare therapy.

Exclusion Criteria:

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Compliance
• Substance Dependence
• Substance-Related Disorders
• Treatment Outcome

Intervention

Behavioral:
• Contracting, Prompting and Reinforcing

Locations

Country	Name	City	State
United States	Salem VA Medical Center, Salem, VA	Salem	Virginia

Sponsors (3)

Lead Sponsor	Collaborator
VA Office of Research and Development	Duke University, Virginia Polytechnic Institute and State University

Country where clinical trial is conducted

United States, 

References & Publications (5)

DeMarce JM, Burden JL, Lash SJ, Stephens RS, Grambow SC. Convergent validity of the Timeline Followback for persons with comorbid psychiatric disorders engaged in residential substance use treatment. Addict Behav. 2007 Aug;32(8):1582-92. Epub 2007 Jan 24. — View Citation

DeMarce JM, Lash SJ, Stephens RS, Grambow SC, Burden JL. Promoting continuing care adherence among substance abusers with co-occurring psychiatric disorders following residential treatment. Addict Behav. 2008 Sep;33(9):1104-12. doi: 10.1016/j.addbeh.2008. — View Citation

Lash J, Burden L, Fearer A. Contracting, Prompting and Reinforcing Substance Abuse Treatment Aftercare Adherence. Journal of Drug Addiction, Education and Eradication. 2007 Jul 1; 2(3/4):455-490.

Lash SJ, Burden JL, Monteleone BR, Lehmann LP. Social reinforcement of substance abuse treatment aftercare participation: Impact on outcome. Addict Behav. 2004 Feb;29(2):337-42. — View Citation

Lash SJ, Stephens RS, Burden JL, Grambow SC, DeMarce JM, Jones ME, Lozano BE, Jeffreys AS, Fearer SA, Horner RD. Contracting, prompting, and reinforcing substance use disorder continuing care: a randomized clinical trial. Psychol Addict Behav. 2007 Sep;21 — View Citation