Substance Dependence Clinical Trial
Official title:
Improving Substance Abuse Treatment Aftercare Adherence and Outcome
Although substance abuse treatment continuing care participation is strongly related to positive treatment outcomes, participation rates are low and few interventions have been developed that improve continuing care adherence and outcome.
Background:
Although substance abuse treatment continuing care participation is strongly related to
positive treatment outcomes, participation rates are low and few interventions have been
developed that improve continuing care adherence and outcome.
Objectives:
The objectives of the study were: 1) to compare the effectiveness of an aftercare
intervention consisting of a participation contract, attendance prompts, and attendance
reinforcers (CPR) to a standard treatment (STX) on adherence to therapy; and 2) to assess
the effects of this intervention on treatment outcome
Methods:
We recruited 150 veterans from the Salem VAMC�s SARRTP who could participate in aftercare.
Our population is similar to those in other VA�s (97% male, 54% Caucasian, 46% minority, 49
years mean age, 44% alcohol dependent only, 56% drug dependent, and 44% with a dual
diagnosis). In this randomized clinical trial, treatment adherence and outcome were measured
at baseline and 3-, 6- and 12-months after participants entered treatment using interviews,
questionnaires, alcohol and drug screens, VA medical records, and therapist ratings. The
study design is a repeated measures nested cohort design, with an intervention and a
standard care group. The primary outcome, abstinence rate, will be analyzed using a logistic
regression model in which the parameters of interest are estimated using Generalized
Estimating Equations (GEE).
Status:
Participant recruitment and follow-up interviews were completed in June 2003 and August
2004, respectively. The HSR&D final report was submitted in April 2005. The main results
paper and additional papers will be submitted for publication in 2005.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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