Clinical Trials Logo
  1. Home
  2. Subfertility
  3. NCT05876234
  4. Details
NCT05876234 Clinical Trial

The Predictive Value of Progesterone

Subfertility Clinical Trial

— PFRET  

Official title:
The Predictive Value of the Progesterone Level on the Day of Embryo Transfer in Cryo Cycles

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT05876234
Other study ID # ONZ-2023-0223
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date April 25, 2023
Est. completion date December 31, 2025

Study information
Verified date June 2024
Source University Hospital, Ghent
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To evaluate a 5 ng/ml serum progesterone (P4) threshold policy for the addition of subcutaneous (SC) P4 in artificially prepared frozen embryo transfer cycles treated with vaginal P4. We assess whether the addition of SC P4 rescues cycles with serum P4 <5 ng/ml and we study the impact of not supplementing cycles with serum P4 >5 ng/ml by comparing them with serum P4 cycles above the conventionally proposed cut-off of 10 ng/ml.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 3000
Est. completion date December 31, 2025
Est. primary completion date December 31, 2025
Accepts healthy volunteers No
Gender Female
Age group 18 Years to 47 Years
Eligibility - Embryo transfer between March 1st 2021 and March 31st 2023 - Determination of progesterone on the day of embryo transfer

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Belgium Ghent University Hospital - Department of Reproductive Medicine Ghent

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Ghent

Country where clinical trial is conducted

Belgium, 

Outcome
Type Measure Description Time frame Safety issue
Primary Ongoing pregnancy rate Fetal heart beat at ultrasound 11 to 13 weeks after last menstruation
Secondary Clinical pregnancy rate Ultrasound visualisation of the gestational sac 6 to 8 weeks after last menstruation
See also
  Status Clinical Trial Phase
Completed NCT03569787 - Hyperprolactinaemia Management in Reproductive Services at University Hospital of Coventry and Warwickshire
Completed NCT03105453 - The Microbiome in Subfertility and Assisted Reproductive Technologies (ART)
Terminated NCT02180256 - Effect of Endometrial Scratching on Assisted Reproduction Outcomes: a Randomized Controlled Trial N/A
Terminated NCT02197832 - A RCT on the Effect of Endometrial Injury on Improving Ongoing Pregnancy Rate in Subfertile Women Undergoing FET Cycles N/A
Completed NCT00971152 - Effect of a Higher Than Maximum 450IU Gonadotropin Dose in an In-vitro Fertilization Cycle Phase 3
Completed NCT01569945 - Hormonal Stimulation in IUI Treatment: Is Clomifen Combined With Ethinyl Estradiol Better, Worse or Equal to Menopur N/A
Recruiting NCT04064840 - GnRH Agonist for Dual Trigger in IVF and for Luteal Phase Support in FET Phase 3
Recruiting NCT02561793 - DHEA Versus Placebo in Women With Poor Ovarian Response Phase 3
Terminated NCT02570386 - Clinical Effectiveness of Frozen Thawed Embryo Transfer Compared to Fresh Embryo Transfer N/A
Completed NCT02197208 - A RCT Comparing Spontaneous Natural Cycles and Human Chorionic Gonadotrophin-induced Natural Cycles in FET N/A
Completed NCT01961336 - Transdermal Testosterone Pretreatment in Poor Responders Undergoing IVF Phase 3
Completed NCT02487940 - Assessment of Intralipid Efficacy in Women With Unexplained Recurrent Implantation Failure Phase 4
Completed NCT01385618 - Gene-polymorphisms Relating to Human Subfertility N/A
Completed NCT00985062 - Mild Versus Conventional Ovarian Stimulation Treatment for In Vitro Fertilization N/A
Recruiting NCT04538560 - Preimplantation Genetic Testing for Aneuploidy of Polar Bodies N/A
Completed NCT02748278 - Comparison of the Number of Oocytes Obtained Between Chinese and Caucasian Women in IVF Treatment
Completed NCT02044445 - Is the IVF Outcome Dependent on the Time Interval Between hCG Administration and Oocyte Retrieval? N/A
Completed NCT02863614 - Analgesia for Endometrial Scratching N/A
Completed NCT02154958 - Role of Follicular Output Rate in the Prediction of in Vitro Fertilization and Intracytoplasmic Sperm Injection in Women With Unexplained Infertility N/A
Completed NCT02151006 - Does Dehydro Epiandrosterone (DHEA) Improve Pregnancy Rate in Women Undergoing IVF/ICSI With Expected Poor Ovarian Response? Phase 3