Endometrial Scratching for Cryopreserved Embryo Transfer

Subfertility Clinical Trial

Official title:

Endometrial Scratching for Cryopreserved Embryo Transfer: a Randomized Controlled Trial

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT02093442
• Other study ID #: CAAE:03292412.0.0000.5440
• Status: Terminated
• Phase: N/A
• Start date: July 2014
• Est. completion date: June 2016

Study information

• Verified date: May 2018
• Source: University of Sao Paulo
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Endometrial injury performed in a cycle preceding the one for embryo transfer is associated with an increased implantation and pregnancy rate when carried out during the month preceding that of ovulation induction and fresh embryo transfer. However, there is no evidence about the effect of this intervention on the transfer of cryopreserved embryos.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 62
• Est. completion date: June 2016
• Est. primary completion date: June 2016
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Age > 18

• At least one cryopreserved embryo

Exclusion Criteria:

Related Conditions & MeSH terms

• Infertility
• Subfertility

Intervention

Procedure:
• Endometrial injury
Endometrial biopsy using a pipelle de Cornier

Locations

Country	Name	City	State
Brazil	Setor de Reprodução Humana - FMRP-USP	Ribeirao Preto	SP

Sponsors (1)

Lead Sponsor	Collaborator
University of Sao Paulo

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Multiple pregnancy	A pregnancy with more than one gestational sac.	3 months
Primary	Live birth	The complete expulsion or extraction from its mother of a product of fertilization, irrespective of the duration of the pregnancy, which, after such separation, breathes or shows any other evidence of life, such as heart beat, umbilical cord pulsation, or definite movement of voluntary muscles, irrespective of whether the umbilical cord has been cut or the placenta is attached.	10 months
Secondary	Clinical pregnancy	A pregnancy diagnosed by ultrasonographic visualization of one or more gestational sacs or definitive clinical signs of pregnancy. It includes ectopic pregnancy. Note: Multiple gestational sacs are counted as one clinical pregnancy.	3 months
Secondary	Miscarriage	The spontaneous loss of a clinical pregnancy	5 months