Clinical Trials Logo
  1. Home
  2. Subclinical Hypothyroidism
  3. NCT02090907

Effects of Levothyroxine on Endothelial Function of Patients With Subclinical Hypothyroidism

Subclinical Hypothyroidism Clinical Trial

Official title:
Effects of Levothyroxine on Endothelial Function of Patients With Subclinical Hypothyroidism

Clinical Trial Summary

Hypothyroidism is risk factor in atherosclerotic cardiovascular diseases, but there is a controversy in effect of subclinical hypothyroidism on cardiovascular diseases. We aim to estimate the relation between subclinical hypothyroidism and endothelial dysfunction and the effects of levothyroxine therapy on it. Patients with confirmed subclinical hypothyroidism by lab results will be randomized to two groups of treatment with one daily dose of 100 mg Levothyroxine or placebo. The flow-mediated dilation and intima media thickness are evaluated before and after the study.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02090907
Study type Interventional
Source Isfahan University of Medical Sciences
Contact
Status Completed
Phase Phase 2/Phase 3
Start date May 2013
Completion date February 2014
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05019118 - Dietary Intervention With Únicla Dairy Products (DANTIAN) N/A
Completed NCT01838031 - Thyroid Screening Protocol During Pregnancy: a Multi-center Prospective Controlled Study N/A
Completed NCT01335802 - Relation Between Subclinical Hypothyroidism and Outcome of Pregnancy
Terminated NCT00962221 - Lipids Profile in Subclinical Hypothyroidism N/A
Completed NCT00388297 - Thyroid Therapy for Mild Thyroid Deficiency in Pregnancy Phase 3
Completed NCT03898622 - Supplementation of Thyroid Hormone for TSH Control in Patients With Chronic Kidney Disease Without TRR. Phase 3
Completed NCT01985204 - Iodine Supplementation in Obesity N/A
Recruiting NCT06041204 - Best Treatment for Women With Both (Polycystic Ovary Syndrome) PCOS and Subclinical Hypothyroidism N/A
Completed NCT01660126 - Thyroid Hormone Replacement for Subclinical Hypothyroidism Phase 4
Completed NCT04354896 - The Effect of Thyroid Hormone Therapy on Muscle Mass and Function in Older Adults With Subclinical Hypothyroidism Phase 4
Completed NCT04288115 - Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyroidism Phase 4
Completed NCT01853579 - The TRUST Study - Depression Substudy Phase 4
Completed NCT00921050 - Subclinical Hypothyroidism and Mind in the Elderly Phase 2/Phase 3
Completed NCT00535561 - Iron Deficiency Anemia Can be an Indication for Treatment of Subclinical Hypothyroidism Phase 1
Completed NCT00498238 - The Effect of Levothyroxine on Arterial Stiffness and Lipid Profile in Patients With Subclinical Hypothyroidism N/A
Completed NCT03036956 - The Prevalence of Sub Clinical Hypothyroidism During Early Pregnancy in Pakistan N/A
Completed NCT02061111 - NeoThyr - the Role of Mitochondria-dysfunction in Newborns of Mothers With Autoimmune Thyroid Disease
Completed NCT01832753 - Treatment Trial of Subclinical Hypothyroidism in Down Syndrome N/A
Completed NCT02399475 - Mechanistic Study of Subclinical Hypothyroidism In the Elderly N/A
Completed NCT00437931 - Color Flow Doppler Ultrasound in Subclinical Thyroid Dysfunction N/A