Clinical Trials Logo

Clinical Trial Summary

Estimate the proper thyroid screening method during pregnancy. Evaluate if maternal subclinical hypothyroidism treatment during pregnancy result in improved pregnancy outcome and cognitive function in the children.


Clinical Trial Description

The investigators conducted a single-blinded trial in which pregnant women at a gestation of less than 12 weeks, usually 6 to 8 weeks, provided blood samples for measurement of thyrotropin, free thyroxine(FT4) and thyroid peroxidase antibody (TPOAb). Women were assigned to a screening group in PUMCH (in which measurements were obtained immediately) or a control group in HMCHH (in which serum was stored and measurements were obtained shortly after delivery). Each group enrolled 1000 pregnant women separately. Women with positive findings in the screening group were given individualized levothyroxine treatment and regular follow-up. Compare the pregnancy outcomes, IQ at 2-3 years of age in children of women with subclinical hypothyroidism between two groups. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01838031
Study type Interventional
Source Peking Union Medical College Hospital
Contact
Status Completed
Phase N/A
Start date September 2011
Completion date September 2013

See also
  Status Clinical Trial Phase
Not yet recruiting NCT05019118 - Dietary Intervention With Únicla Dairy Products (DANTIAN) N/A
Completed NCT01335802 - Relation Between Subclinical Hypothyroidism and Outcome of Pregnancy
Terminated NCT00962221 - Lipids Profile in Subclinical Hypothyroidism N/A
Completed NCT00388297 - Thyroid Therapy for Mild Thyroid Deficiency in Pregnancy Phase 3
Completed NCT03898622 - Supplementation of Thyroid Hormone for TSH Control in Patients With Chronic Kidney Disease Without TRR. Phase 3
Completed NCT01985204 - Iodine Supplementation in Obesity N/A
Recruiting NCT06041204 - Best Treatment for Women With Both (Polycystic Ovary Syndrome) PCOS and Subclinical Hypothyroidism N/A
Completed NCT04354896 - The Effect of Thyroid Hormone Therapy on Muscle Mass and Function in Older Adults With Subclinical Hypothyroidism Phase 4
Completed NCT01660126 - Thyroid Hormone Replacement for Subclinical Hypothyroidism Phase 4
Completed NCT02090907 - Effects of Levothyroxine on Endothelial Function of Patients With Subclinical Hypothyroidism Phase 2/Phase 3
Completed NCT04288115 - Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyroidism Phase 4
Completed NCT01853579 - The TRUST Study - Depression Substudy Phase 4
Completed NCT00921050 - Subclinical Hypothyroidism and Mind in the Elderly Phase 2/Phase 3
Completed NCT00535561 - Iron Deficiency Anemia Can be an Indication for Treatment of Subclinical Hypothyroidism Phase 1
Completed NCT00498238 - The Effect of Levothyroxine on Arterial Stiffness and Lipid Profile in Patients With Subclinical Hypothyroidism N/A
Completed NCT03036956 - The Prevalence of Sub Clinical Hypothyroidism During Early Pregnancy in Pakistan N/A
Completed NCT02061111 - NeoThyr - the Role of Mitochondria-dysfunction in Newborns of Mothers With Autoimmune Thyroid Disease
Completed NCT01832753 - Treatment Trial of Subclinical Hypothyroidism in Down Syndrome N/A
Completed NCT02399475 - Mechanistic Study of Subclinical Hypothyroidism In the Elderly N/A
Completed NCT00437931 - Color Flow Doppler Ultrasound in Subclinical Thyroid Dysfunction N/A