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Clinical Trial Summary

The OSSIOfiber® Trimmable Fixation Nails are indicated for maintenance of alignment and fixation of bone fractures, osteotomies, arthrodesis and bone grafts in the presence of appropriate additional immobilization (e.g., rigid fixation implants, cast, brace). Our hypothesis is that the use of OSSIOfiber® Trimmable Fixation Nails for treating subchondral insufficiency of the knee will result in improvement of patient-reported outcomes and imaging findings. The primary objective of this study is to evaluate the effectiveness of implanting bio-integrative OSSIOfiber® Trimmable Fixation Nails, organized in a bi-cortical rafter formation within the tibia or femur for the management of subchondral insufficiency. The OSSIOfiber® Trimmable Fixation Nails used in this study will be considered on-label.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT06423378
Study type Interventional
Source Vanderbilt University Medical Center
Contact Lindsey Agnew, MS
Phone 6158751996
Email lindsey.agnew@vumc.org
Status Not yet recruiting
Phase Phase 2
Start date July 3, 2024
Completion date December 3, 2025