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Clinical Trial Summary

Intensive care patients with established invasive intracranial neuromonitoring due to neurotrauma are subjected to a repeated non-invasive sonographic recording of the optic-nerve-sheath-diameter (ONSD). The recorded images are analyzed through a machine-learning-algorithm and an experienced ultrasound operator. Results are correlated to the parallel recorded intracranial pressure (ICP). The study aims to establish ONSD as a supplementary for raised ICP.


Clinical Trial Description

During the intensive care stay, patients with implemented invasive intracranial pressure monitoring will have sonographic recording of the optic nerve sheath (video clip) with a parallel recording of the underlying ICP. The obtained image material is then i) analyzed by a machine-learning algorithm and ii) manually by 2 blinded differently experienced examiners (expert, novice) with respect to the ONSD. For the manual procedure, three individual measurements are made for each eye and the mean value is determined. Subsequently, the measured values of the two examiners and the automated procedure are correlated with the ICP recorded during the sonographic examination. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05818371
Study type Interventional
Source University Hospital Tuebingen
Contact Jonas Tellermann, MD
Phone +4970712968685
Email Jonas.Tellermann@med.uni-tuebingen.de
Status Not yet recruiting
Phase N/A
Start date May 1, 2023
Completion date March 2024

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