Genome-wide Analysis of Single Nucleotide Polymorphisms of Brain Arteriovenous Malformations and Cerebral Aneurysm

Subarachnoid Hemorrhage Clinical Trial

Official title:

Genome-wide Analysis of Single Nucleotide Polymorphisms of Brain Arteriovenous Malformations and Cerebral Aneurysm

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT01801488
• Other study ID #: IRB#238810
• Status: Terminated
• Phase: N/A
• First received: December 12, 2012
• Last updated: November 24, 2015
• Start date: November 2011

Study information

• Verified date: February 2013
• Source: State University of New York - Upstate Medical University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Test single nucleotide polymorphisms (SNP's) in ruptured and unruptured aneurysm tissue to identify a genetic difference between the two types of aneurysms; and to test SNP's in arteriovenous malformation tissue to identify a genetic link.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 5
• Est. primary completion date: March 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 89 Years

Eligibility

Inclusion Criteria:

• All adult patients between the ages of 18 and 89 that are having open surgical resection of an AVM or clipping of an aneurysm will be included

Exclusion Criteria:

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Aneurysm
• Arteriovenous Malformations
• Congenital Abnormalities
• Hemangioma
• Intracranial Aneurysm
• Subarachnoid Hemorrhage

Locations

Country	Name	City	State
United States	SUNY Upstate Medical University	Syracuse	New York

Sponsors (1)

Lead Sponsor	Collaborator
State University of New York - Upstate Medical University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Risk gene expression	The samples will be frozen after collection and then analyzed.	Within one week of sample collection.	No