Subarachnoid Hemorrhage, Aneurysmal Clinical Trial
Official title:
Response of Intracranial Pressure Based on Head-of-Bed Positioning in Aneurysmal Subarachnoid Hemorrhage
The purpose of this study is to evaluate how pressure inside the skull responds to position changes in patients with brain bleeds.
The optimal positioning of the head-of-bed (HOB) has remained controversial in the neurosurgical field. Very limited data exists outlining the effects of HOB positioning in subarachnoid hemorrhage (SAH) patients. One study by Schulz-Stubner and Thiex assess the effects of HOB positioning in SAH and traumatic brain injury (TBI) patients. While this study offers some valuable insight into the changes in cerebral hemodynamics seen when the HOB changes, it congregates data from two very different pathologies. This could potentially misrepresent the true effects patients experience. A study by Kung et al. assesses cerebral blood flow dynamics and HOB changes in the setting of SAH but does not evaluate the effects on intracranial pressure (ICP) (Kung, et al., 2013). There appear to be no studies which evaluate the effect of HOB positioning on ICP in patients with SAH. No current data exists to determine if dependent leg positioning would help to further lower ICP. Theoretically, placing a patient's legs in a dependent position would lead to increased venous pooling of blood in the legs which might translate to lower ICP. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT06032533 -
Remote Ischemic Conditioning in Aneurysmal SAH
|
N/A | |
Completed |
NCT05131295 -
Dapsone Use in Patients With Aneurysmal Subarachnoid Hemorrhage.
|
Phase 3 | |
Recruiting |
NCT04583163 -
Variability in Transcranial Doppler Technique in Neuro-Critical Care Patients
|
||
Recruiting |
NCT06006975 -
Early Warning of Delayed Cerebral Ischemia
|
||
Terminated |
NCT02893826 -
Safety/Pharmacokinetic Study Comparing Intracisternal EG-1962 to Standard of Care Enteral Nimodipine in Adults With aSAH
|
Phase 1 | |
Unknown status |
NCT01567449 -
Risk Factors for Aneurysm Rebleeding
|
N/A | |
Recruiting |
NCT05095857 -
The Anesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury
|
Phase 4 | |
Not yet recruiting |
NCT04512859 -
Stellate Ganglion Block in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage
|
N/A | |
Recruiting |
NCT05103566 -
Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage
|
N/A | |
Not yet recruiting |
NCT04696523 -
Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage
|
Phase 2 | |
Completed |
NCT04415736 -
Artificial Intelligence in Subarachnoid Hemorrhage
|
||
Recruiting |
NCT05925478 -
Pterygopalatine Fossa Block in Aneurysmal Subarachnoid Hemorrhage
|
Early Phase 1 | |
Recruiting |
NCT04649398 -
Cerebral Nimodipine Concentrations Following Oral, Intra-venous and Intra-arterial Administration
|
||
Recruiting |
NCT02995928 -
Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage
|
N/A | |
Recruiting |
NCT04945603 -
Poor Grade Aneurysmal Subarachnoid Hemorrhage Study Group
|
||
Active, not recruiting |
NCT06239142 -
Understanding Mental Fatigue After Subarachnoid Hemorrhage
|
||
Completed |
NCT03318783 -
Subarachnoid Hemorrhage and Soluble Epoxide Hydrolase Inhibition Trial
|
Phase 1/Phase 2 | |
Terminated |
NCT05686265 -
Cerebral Nitrosative/Oxidative Stress in Aneurysmal Subarachnoid Haemorrhage
|
||
Not yet recruiting |
NCT06359782 -
Complement Inhibition: Attacking the Overshooting Inflammation @Fter Subarachnoid Hemorrhage (CIAO@SAH)
|
Phase 2 | |
Not yet recruiting |
NCT06057155 -
Intracranial Pressure and Optic Nerve Sheath Diameter With CLOSED Bundle
|