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Magnesium Treating Subarachnoid Hemorrhage Vasospasm — MATSH-SHapE  

Subarachnoid Hemorrhage, Aneurysmal Clinical Trial

Official title:
Magnesium in Treating Subarachnoid Hemorrhage Related Vasospasm, A Haptoglobin Genomic Based Randomized Controlled Trial

Clinical Trial Summary

A randomized clinical trial investigating magnesium sulphate ability to reduce risk of cerebral vasospasm after acute subarachnoid hemorrhage hence improving outcome particularly in haptoglobin 2-2 patients who are highly susceptible for severe complications after subarachnoid hemorrhage.

Clinical Trial Description

Study Design and Location: Investigators propose a double blinded, randomized (1:1), placebo-controlled, multicenter, clinical trial including patients with acute aSAH. Participants will be allocated either to MgSO4 or placebo. The permission to conduct the study protocol will be considered for approval by the ethics committee of General Committee of Teaching Hospitals and Institutes (GCTHI), Egypt. The study will be conducted in 3 centers; El-Materia Educational Hospital, Ain Shams University Hospitals and Nasr City Insurance Hospital. The assigned centers for this study represent large-volume referral stroke centers that provide comprehensive management protocols for aSAH. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04613960
Study type Interventional
Source General Committee of Teaching Hospitals and Institutes, Egypt
Contact Ahmed M Ateia
Phone +201202474777
Email a_ateia@hotmail.com
Status Not yet recruiting
Phase Phase 2/Phase 3
Start date December 2022
Completion date June 2024
View Details
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