Subacute Myocardial Infarction Clinical Trial
Official title:
An Open-label, Non-Randomized, Multi-Center Study to Assess the Safety and Cardiovascular Effects of Autologous ADSC Implantation by a Catheter Delivery System In Patients During the Subacute Recovery Phase of ST-Elevation MI
The intent of this clinical study is to answer the questions: 1) Is the proposed treatment safe? and 2) Is treatment effective in improving cardiac function and clinical outcomes?
This will be an open-label, non-randomized multi-center study of ASC implantation using a
catheter delivery system. ASCs will be derived from the patient's adipose-derived tissue.
Liposuction will be performed to collect the adipose tissue specimen for subsequent
processing to isolate the stem cells. The injection catheter will be used for delivery of the
ASCs therapy.
The adipose tissue specimen will be collected mainly from the patient's abdomen using a
liposuction cannula. The adipose tissue may be collected from other areas if necessary The
adipose tissue is transferred to the laboratory for separation of the adipose tissue-derived
stem cells, which are then transferred to an injection/infusion catheter for delivery into
the akinetic myocardial scar in the region of a previous infarct
;